T
Tom Feys
Researcher at Ghent University Hospital
Publications - 9
Citations - 698
Tom Feys is an academic researcher from Ghent University Hospital. The author has contributed to research in topics: Engineering & Computer science. The author has an hindex of 5, co-authored 5 publications receiving 681 citations.
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Journal ArticleDOI
High-throughput stem-loop RT-qPCR miRNA expression profiling using minute amounts of input RNA
Pieter Mestdagh,Tom Feys,Nathalie Bernard,Simone Guenther,Caifu Chen,Franki Speleman,Jo Vandesompele +6 more
TL;DR: In this paper, the Megaplex reverse transcription format of the stem-loop primer-based real-time quantitative polymerase chain reaction (RT-qPCR) approach was used to quantify miRNA expression.
High-throughput stem-loop RT-PCR miRNA expression profiling using minute amounts of input RNA
Pieter Mestdagh,Tom Feys,Nathalie Bernard,Simone Guenther,Caifu Chen,Vladimir Benes,Franki Speleman,Jo Vandesompele +7 more
TL;DR: The successful evaluation of the Megaplex reverse transcription format of the stem-loop primer-based real-time quantitative polymerase chain reaction (RT-qPCR) approach to quantify miRNA expression is presented, ensuring high-throughput detection.
Journal ArticleDOI
Comparison of miRNA profiles of microdissected Hodgkin/Reed-Sternberg cells and Hodgkin cell lines versus CD77+ B-cells reveals a distinct subset of differentially expressed miRNAs.
Pieter Van Vlierberghe,An De Weer,Pieter Mestdagh,Tom Feys,Katleen De Preter,Pascale De Paepe,Kathleen Lambein,Jo Vandesompele,Nadine Van Roy,Bruno Verhasselt,Bruce Poppe,Frank Speleman +11 more
TL;DR: The data suggest that miRNAs are implicated in the pathogenesis of Hodgkin lymphoma and prompt further investigations concerning their role in cHL.
Journal ArticleDOI
A detailed inventory of DNA copy number alterations in four commonly used Hodgkin’s lymphoma cell lines
Tom Feys,Bruce Poppe,Katleen De Preter,Nadine Van Roy,Bruno Verhasselt,Pascale De Paepe,Anne De Paepe,Franki Speleman +7 more
TL;DR: ACGH was performed on four cHL cell lines leading to the improved delineation of known chromosomal imbalances and the detection of 35 hitherto undetected aberrations.