T
Tony J. Collins
Researcher at McMaster University
Publications - 48
Citations - 6570
Tony J. Collins is an academic researcher from McMaster University. The author has contributed to research in topics: Stem cell & Induced pluripotent stem cell. The author has an hindex of 27, co-authored 47 publications receiving 5956 citations. Previous affiliations of Tony J. Collins include University of Edinburgh & Babraham Institute.
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ImageJ for microscopy
TL;DR: The near-comprehensive range of import filters that allow easy access to image and meta-data, a broad suite processing and analysis routine, and enthusiastic support from a friendly mailing list are invaluable for all microscopy labs and facilities-not just those on a budget.
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2-aminoethoxydiphenyl borate (2-APB) is a reliable blocker of store-operated Ca2+ entry but an inconsistent inhibitor of InsP3-induced Ca2+ release.
Martin D. Bootman,Tony J. Collins,Lauren Mackenzie,H. Llewelyn Roderick,Michael J. Berridge,Claire M. Peppiatt +5 more
TL;DR: 2‐Aminoethoxydiphenyl borate is a reliable blocker of store‐operated Ca2+ entry but an inconsistent inhibitor of InsP3‐induced Ca 2+ release.
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Mitochondria are morphologically and functionally heterogeneous within cells
TL;DR: The data indicate that mitochondria within individual cells are morphologically heterogeneous and unconnected, allowing them to have distinct functional properties.
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Calcium signalling—an overview
Martin D. Bootman,Tony J. Collins,Claire M. Peppiatt,Larissa S Prothero,Lauren Mackenzie,Patrick De Smet,Marianne Travers,Stephen C. Tovey,Jeong T. Seo,Michael J. Berridge,Francesca Ciccolini,Peter Lipp +11 more
TL;DR: To generate the variety of observed Ca2+ signals, different cell types employ components selected from aCa2+ signalling 'toolkit', which comprizes an array of signalling, homeostatic and sensory mechanisms.
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Identification of Drugs Including a Dopamine Receptor Antagonist that Selectively Target Cancer Stem Cells
Eleftherios Sachlos,Ruth M. Risueño,Sarah Laronde,Zoya Shapovalova,Jong-Hee Lee,Jennifer Russell,Monika Malig,Jamie D. McNicol,Aline Fiebig-Comyn,Monica Graham,Marilyne Levadoux-Martin,Jung Bok Lee,Andrew O. Giacomelli,John A. Hassell,Daniela Fischer-Russell,Michael Trus,Ronan Foley,Brian Leber,Anargyros Xenocostas,Eric D. Brown,Tony J. Collins,Mickie Bhatia +21 more
TL;DR: It is suggested that dopamine receptors may serve as a biomarker for diverse malignancies, demonstrate the utility of using neoplastic hPSCs for identifying CSC-targeting drugs, and provide support for the use of differentiation as a therapeutic strategy.