Toshikatsu Shinka

TL;DR: A translocation breakpoint in a PPD patient and a transgenic insertion site in the polydactylous mouse mutant sasquatch reveals that the Lmbr1 gene is incidental to the phenotype and that the mutation directly interrupts a cis-acting regulator of Shh, most likely the target for generating PPD mutations in human.

TL;DR: The distribution pattern of Y-chromosomal haplogroups reveals the complex origin of the Koreans, resulting from genetic contributions involving the northern Asian settlement and range expansions mostly from southern-to-northern China.

TL;DR: The results of this study demonstrated that activation of ras genes due to point mutations in chromate-related lung cancer is a rare event and Ras oncogenes activated by point mutations do not have a major role in the process of tumorigenesis of chromATE- related lung cancer.

TL;DR: A novel method for sex identification, using a denaturing high-performance liquid chromatography (DHPLC) system, which may have wide applications in many different fields, such as forensic medicine, prenatal diagnosis, inbreeding of animals, and anthropology.

TL;DR: The findings suggested that linkage studies between Y-specific markers are helpful in understanding the migratory patterns in East Asia and suggested that Japanese males have characteristically different Y-chromosomes compared with other populations.