T
Toshio Mazda
Researcher at Gulf Coast Regional Blood Center
Publications - 43
Citations - 1839
Toshio Mazda is an academic researcher from Gulf Coast Regional Blood Center. The author has contributed to research in topics: Hepatitis C virus & Hepatitis. The author has an hindex of 16, co-authored 43 publications receiving 1794 citations.
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Journal ArticleDOI
Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma.
TL;DR: Its adipocyte-specific expression suggests that GBP28 may function as an endogenous factor involved in lipid catabolism and storage or whole body metabolism, and appears to belong to a family of proteins possessing a collagen-like domain through which they form homo-trimers, which further combine to make oligomeric complexes.
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Purification and Characterization of a Novel Hyaluronan-Binding Protein (PHBP) from Human Plasma: It Has Three EGF, a Kringle and a Serine Protease Domain, Similar to Hepatocyte Growth Factor Activator
Nam-Ho Choi-Miura,Takashi Tobe,Jun-ichi Sumiya,Yasuko Nakano,Yoshihiro Sano,Toshio Mazda,Motowo Tomita +6 more
TL;DR: The amino acid sequence deduced from the nucleotide sequence of the cloned PHBP cDNA exhibited significant homology to that of hepatocyte growth factor activator (HGFA), indicating that PHBP was a novel hyaluronan-binding protein in human plasma.
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Discrimination of human hla‐drb1 alleles by pcr‐sscp (single‐strand conformation polymorphism) method
Makoto Bannai,K. Tokunaga,Ling Lin,S. Kuwata,Toshio Mazda,Ichita Amaki,Kiyoshi Fujisawa,Takeo Juji +7 more
TL;DR: The single‐strand conformation polymorphism (PCR‐SSCP) method has been adopted for discrimination of human HLA‐DRB1 alleles and is useful in the screening of ‘new’ alleles as well as the donor‐recipient molecular matching of HLA class II genes for various purposes, e.g. selection of bone marrow transplant donors.
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A serum protein SP40,40 modulates the formation of membrane attack complex of complement on erythrocytes.
TL;DR: It is indicated that SP40,40 modulates the formation of membrane attack complex by interacting with C56f at the first step, and that the co-existence of other factors, besides C 56f, is required for the enhancing activity of SP40.40.
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Predictive value of screening tests for persistent hepatitis C virus infection evidenced by viraemia. Japanese experience.
Junnosuke Watanabe,Chieko Matsumoto,Kuniko Fujimura,T. Shimada,Kusuya Nishioka,Hiroshi Yoshizawa,Hiroaki Okamoto,Hisao Iizuka,T. Tango,Hisami Ikeda,N. Endo,Toshio Mazda,T. Nojiri,K. Aoyama,K. Kanemitsu,Hiroyuki Yamano,Masaaki Mizui,F. Yokoishi,Katsushi Tokunaga +18 more
TL;DR: Passive haemagglutination and particle agglutination (PHA and PA) tests were highly effective to predict HCV viraemia among blood donors and can easily determine antibody titre.