T
Toshio Nishikawa
Researcher at Nagoya University
Publications - 285
Citations - 4841
Toshio Nishikawa is an academic researcher from Nagoya University. The author has contributed to research in topics: Moiety & Dynemicin A. The author has an hindex of 35, co-authored 265 publications receiving 4435 citations. Previous affiliations of Toshio Nishikawa include National Presto Industries & National Tsing Hua University.
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Activated human T cells directly induce osteoclastogenesis from human monocytes: possible role of T cells in bone destruction in rheumatoid arthritis patients.
Shigeru Kotake,Nobuyuki Udagawa,Masayuki Hakoda,Makio Mogi,Kazuki Yano,Eisuke Tsuda,Ken Takahashi,Takefumi Furuya,Shigeru Ishiyama,Kang-Jung Kim,Seiji Saito,Toshio Nishikawa,Naoyuki Takahashi,Akifumi Togari,Taisuke Tomatsu,Tatsuo Suda,Naoyuki Kamatani +16 more
TL;DR: The present findings suggest that excess production of RANKL by activated T cells increases the level of sRANKL in synovial fluid and may contribute to osteoclastic bone resorption in RA patients, the first to demonstrate osteoclastogenesis using human-derived T cells and monocytes.
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Active Remodeling of the Coronary Arterial Lesions in the Late Phase of Kawasaki Disease Immunohistochemical Study
Atsuko Suzuki,Sachiko Miyagawa-Tomita,Keiko Komatsu,Toshio Nishikawa,Yasunari Sakomura,Toshinobu Horie,Makoto Nakazawa +6 more
TL;DR: In this article, the authors examined formalin-fixed specimens of the coronary arteries immunohistochemically by using antibodies against vascular growth factors (GFs) and their receptors in 7 children with Kawasaki disease, 9 children with no coronary disease, and 3 adults with atherosclerosis.
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First Asymmetric Total Synthesis of Tetrodotoxin
TL;DR: This work has achieved the first asymmetric total synthesis from 2-acetoxy-tri-O-acetyl-d-glucal as a chiral starting material and selected the protective groups to accomplish the total synthesis of tetrodotoxin in an enantiomerically pure form.
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Nitric oxide contributes to the progression of myocardial damage in experimental autoimmune myocarditis in rats.
Shigeru Ishiyama,Michiaki Hiroe,Toshio Nishikawa,Shinji Abe,Takashi Shimojo,Hiroshi Ito,Sakae Ozasa,Katsutoshi Yamakawa,Masunori Matsuzaki,Minhaz Uddin Mohammed,Hiroe Nakazawa,Takeshi Kasajima,Fumiaki Marumo +12 more
TL;DR: Excess amounts of NO produced by iNOS appear to contribute to the progression of myocardial damage in myocarditis, and AG may prove to be useful in the treatment ofmyocarditis.
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Tenascin-C is a useful marker for disease activity in myocarditis.
Kyoko Imanaka-Yoshida,Michiaki Hiroe,Yasuhiro Yasutomi,Tetsuya Toyozaki,Takuro Tsuchiya,Naomi Noda,Toshiki Maki,Toshio Nishikawa,Teruyo Sakakura,Toshimichi Yoshida +9 more
TL;DR: It is demonstrated that TNC is a useful marker for evaluation of disease activity in myocarditis, with the expression level correlating with histological evidence of inflammatory activity at a very early stage.