Tracey L. Smith

TL;DR: The identification of tumor-specific receptors through combinatorial phage display technology and the use of antibody display selection to identify recombinant human scFvs against these tumor- specific receptors are summarized.

TL;DR: The demonstration that a known, short, biologically active motif can direct tumor targeting and receptor-mediated internalization of AAVP particles may streamline the potential utility of myriad other short peptide motifs and provide a blueprint for therapeutic applications in a variety of cancers and perhaps many nonmalignant diseases as well.

TL;DR: A next-generation of targeted AAVP vectors are designed, developed, and validated that mitigate obstacles to efficient gene delivery through the cis-genetic incorporation of specific peptide motifs to the phage capsid and enable improved targeted gene delivery to tumor cells.

TL;DR: In this paper, two targeted phage-based vaccination approaches against SARS-CoV-2: dual ligand peptide-targeted phage and adeno-associated virus/phage (AAVP) particles.

TL;DR: It is established that RAGE-PR3 interaction mediates homing of prostate cancer cells to the bone marrow, and potential implications for prognosis and therapeutic intervention are established.