T
Tsutomu Fujimura
Researcher at University of Salamanca
Publications - 36
Citations - 1749
Tsutomu Fujimura is an academic researcher from University of Salamanca. The author has contributed to research in topics: RNA & RNA-dependent RNA polymerase. The author has an hindex of 20, co-authored 36 publications receiving 1561 citations. Previous affiliations of Tsutomu Fujimura include Spanish National Research Council & National Institutes of Health.
Papers
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Journal ArticleDOI
Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5′-diphosphates
Delphine Goubau,Martin Schlee,Safia Deddouche,Andrea J. Pruijssers,Thomas Zillinger,Marion Goldeck,Christine Schuberth,Annemarthe G. van der Veen,Tsutomu Fujimura,Jan Rehwinkel,Jason A. Iskarpatyoti,Winfried Barchet,Janos Ludwig,Terence S. Dermody,Gunther Hartmann,Caetano Reis e Sousa +15 more
TL;DR: It is shown that RIG-I also mediates antiviral responses to RNAs bearing 5′-diphosphates (5′pp), indicating that recognition of 5′pp-RNA acts as a powerful means of self/non-self discrimination by the innate immune system.
Journal ArticleDOI
Portable encapsidation signal of the L-A double-stranded RNA virus of S. cerevisiae
TL;DR: The (+) single-stranded RNA of the L-A virus is the species packaged to form new viral particles, and a sequence 400 bases from the 3' end is necessary for this activity to bind viral (+) ssRNA.
Book ChapterDOI
Viruses and prions of Saccharomyces cerevisiae.
TL;DR: This work emphasizes the L-A dsRNA virus and its killer-toxin-encoding satellites, the 20S and 23S ssRNA naked viruses, and the several infectious proteins (prions) of yeast.
Journal ArticleDOI
Gene overlap results in a viral protein having an RNA binding domain and a major coat protein domain
Tsutomu Fujimura,Reed B. Wickner +1 more
TL;DR: The 180 kd protein is also encoded by L-A dsRNA and consists of a major coat protein domain and a ssRNA binding domain, which is found that the isolated binding complex replicates only if it was formed in the presence of the host factor.
Journal ArticleDOI
Pol of gag-pol fusion protein required for encapsidation of viral RNA of yeast L-A virus.
TL;DR: It is shown that Gag alone is sufficient for virus particle formation, but that it fails to package the viral single-stranded RNA genome, consistent with the L-A virus encapsidation model.