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Ulrike Köck

Researcher at Medical University of Vienna

Publications -  6
Citations -  219

Ulrike Köck is an academic researcher from Medical University of Vienna. The author has contributed to research in topics: Hippocampal formation & Cytotoxic T cell. The author has an hindex of 4, co-authored 5 publications receiving 107 citations.

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Microglial nodules provide the environment for pathogenic T cells in human encephalitis

TL;DR: Results point towards activation of endosomal TLRs, resulting in increased interferon signaling, inflammasome activation, and chemokine upregulation as early steps in RE pathogenesis.
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The formation of a glial scar does not prohibit remyelination in an animal model of multiple sclerosis.

TL;DR: It is concluded that remyelination occurs despite an abundant glial reaction in this animal model, which indicates a finely regulated, balanced astrocytic involvement leading to successful repair.
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Differences in T cell cytotoxicity and cell death mechanisms between progressive multifocal leukoencephalopathy, herpes simplex virus encephalitis and cytomegalovirus encephalitis

TL;DR: It is suggested that in HSVE and CMVE, cells die by caspase-mediated apoptosis induced by cytotoxic T cells, while in PML, infected cells are not eliminated by the immune system but seem to die by virus-induced PARP and AIF translocation in a type of cell death defined as parthanatos.
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T cell numbers correlate with neuronal loss rather than with seizure activity in medial temporal lobe epilepsy.

TL;DR: In this paper, the presence of T cells in various subgroups of Medial Temporal lobe Epilepsy (MTLE) was analyzed and it was shown that T cell numbers were significantly elevated in MTLE compared to healthy controls.