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Ushashree Divakar

Researcher at Nanyang Technological University

Publications -  14
Citations -  745

Ushashree Divakar is an academic researcher from Nanyang Technological University. The author has contributed to research in topics: Digital health & Systematic review. The author has an hindex of 8, co-authored 14 publications receiving 471 citations. Previous affiliations of Ushashree Divakar include Genome Institute of Singapore.

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Journal ArticleDOI

The humanistic and economic burden of chronic wounds: A systematic review.

TL;DR: A systematic review of chronic wounds revealed that health‐related quality of life was lowest for physical pathologies, and based on average estimates were scores most inferior in the domain physical role for both patients with chronic wounds and for those with wound‐related amputations.
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Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm.

TL;DR: It is demonstrated here that genomic redistribution of Oct4 by alternative partnering with Sox2 and Sox17 is a fundamental regulatory event of endodermal specification and provides insights in understanding cell fate transcriptional regulation by highlighting the direct link between the DNA sequence of an enhancer and a developmental outcome.
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Sox transcription factors require selective interactions with Oct4 and specific transactivation functions to mediate reprogramming.

TL;DR: Results suggest that the glutamate (E) to lysine (K) mutation in the HMG domain is necessary but insufficient to swap the function of Sox factors, and the H MG domain alone fused to the VP16 transactivation domain is able to induce reprogramming, albeit at low efficiency.
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Melatonin and health: an umbrella review of health outcomes and biological mechanisms of action.

TL;DR: Melatonin has been shown to be associated with a wide variety of health outcomes in clinically and methodologically heterogeneous populations and many reviews stressed the need for more high-quality randomised clinical trials to reduce the existing uncertainties.
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Review of the potential health effects of light and environmental exposures in underground workplaces

TL;DR: The literature on the range of possible environmental exposures, and the possible health effects, to identify future research directions was narratively reviewed to expand knowledge of the health effects of underground environments.