U
Uwe Claussen
Researcher at University of Jena
Publications - 164
Citations - 6250
Uwe Claussen is an academic researcher from University of Jena. The author has contributed to research in topics: Fluorescence in situ hybridization & Karyotype. The author has an hindex of 42, co-authored 164 publications receiving 6098 citations. Previous affiliations of Uwe Claussen include Schiller International University & University of Erlangen-Nuremberg.
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Cloning defined regions of the human genome by microdissection of banded chromosomes and enzymatic amplification
TL;DR: The dissection of the Langer-Giedion syndrome region on chromosome 8 from GTG-banded metaphase chromosomes and the universal enzymatic amplification of the dissected DNA is described, demonstrating that thousands of region-specific probes can be isolated within ten days.
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Small supernumerary marker chromosomes (sSMC) in humans.
TL;DR: An overview of small supernumerary marker chromosomes is presented, including the first attempt to address problems of nomenclature and their modes of formation, problems connected with mosaicism plus familial occurrence and a short review of the up-to-date approaches available for sSMC characterization.
Journal ArticleDOI
Microdissection based high resolution multicolor banding for all 24 human chromosomes.
Thomas Liehr,Anita Heller,Heike Starke,Nikolai Rubtsov,Vladimir A. Trifonov,Kristin Mrasek,Anja Weise,Alma Kuechler,Uwe Claussen +8 more
TL;DR: The MCB-technique is a high resolution alternative to other FISH based chromosome banding approaches and suited to clarify, which changes appeared in complex chromosomal rearrangements.
Journal ArticleDOI
High resolution multicolor-banding: a new technique for refined FISH analysis of human chromosomes.
TL;DR: A new multicolor-banding technique has been developed which allows the differentiation of chromosome region specific areas at the band level based on the use of differently labeled overlapping microdissection libraries.
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Genotypic and Phenotypic Spectrum in Tricho-Rhino-Phalangeal Syndrome Types I and III
H.-J. Lüdecke,J. Schaper,Peter Meinecke,P. Momeni,Stephanie Groß,D. von Holtum,H. Hirche,Marc Abramowicz,Beate Albrecht,C. Apacik,H.-J. Christen,Uwe Claussen,Koenraad Devriendt,E. Fastnacht,A. Forderer,Ursula Friedrich,Timothy H.J. Goodship,M. Greiwe,Henning Hamm,Raoul C.M. Hennekam,Georg Klaus Hinkel,Maria Hoeltzenbein,Hülya Kayserili,Frank Majewski,Michèle Mathieu,R. McLeod,Alina T. Midro,Ute Moog,Toshiro Nagai,Norio Niikawa,Karen Helene Ørstavik,E. Plöchl,Cornelia S. Seitz,Joerg Schmidtke,Lisbeth Tranebjærg,Masato Tsukahara,Bärbel Wittwer,Bernhard Zabel,Gabriele Gillessen-Kaesbach,B. Horsthemke +39 more
TL;DR: The data indicate that TRPS III is at the severe end of theTRPS spectrum and that it is most often caused by a specific class of mutations in the TRPS1 gene.