V. Chandana Epa

TL;DR: Quantitative Structure Property Relationship Modeling of Diverse Materials Properties Tu Le, V. Chandana Epa, Frank R. Burden, and David A. Winkler.

TL;DR: The structure reveals the domain arrangement in the disulphide-linked ectodomain dimer, showing that the insulin receptor adopts a folded-over conformation that places the ligand-binding regions in juxtaposition, very different from previous models.

TL;DR: Results show that Met can sense the JH signal through direct, specific binding, thus establishing a unique class of intracellular hormone receptors.

TL;DR: In this article, a quantitative measure for charge complementarity and electrostatic complementarity was developed and used to investigate protein-protein interfaces in a rigorous manner, and the results demonstrated the relevance of the long-range effects of charges, as described by the electrostatic potential at the binding interface.

TL;DR: The structure of PsaA is the first structure obtained for an ABC-type binding protein from a Gram-positive organism and lacks the characteristic 'hinge peptides' involved in conformational change upon solute uptake and release.