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V. Chiarion-Sileni

Researcher at University of Sydney

Publications -  24
Citations -  591

V. Chiarion-Sileni is an academic researcher from University of Sydney. The author has contributed to research in topics: Ipilimumab & Nivolumab. The author has an hindex of 11, co-authored 22 publications receiving 546 citations.

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Immunization with recombinant MAGE-A3 protein combined with adjuvant systems AS15 or AS02B in patients with unresectable and progressive metastatic cutaneous melanoma: A randomized open-label phase II study of the EORTC Melanoma Group (16032- 18031)

TL;DR: The MAGE-A3 antigen, expressed in ±60% of metastatic melanomas, is a target of anti-tumor CD4+ and CD8+ T-cells and it is shown that this antigen acts as a ‘spatially aggregating force’ to drive T-cell reprograming in these patients.