V
V. Kuo-LeBlanc
Researcher at Brown University
Publications - 8
Citations - 795
V. Kuo-LeBlanc is an academic researcher from Brown University. The author has contributed to research in topics: Basic fibroblast growth factor & Senile plaques. The author has an hindex of 7, co-authored 8 publications receiving 725 citations. Previous affiliations of V. Kuo-LeBlanc include Rhode Island Hospital & Boston University.
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Journal ArticleDOI
Pathologic evaluation of the human suprachiasmatic nucleus in severe dementia.
Edward G. Stopa,Ladislav Volicer,V. Kuo-LeBlanc,David G. Harper,Devayani Lathi,Barbara A. Tate,Andrew Satlin +6 more
TL;DR: Evidence is provided that both vasopressin and neurotensin neurons are lost in Alzheimer disease, and that the astrocyte/neuron ratio is a reliable indicator of disease-related pathology within the SCN.
Journal ArticleDOI
Agrin and microvascular damage in Alzheimer's disease.
Tyler M. Berzin,Brian D. Zipser,Michael S. Rafii,V. Kuo-LeBlanc,George D. Yancopoulos,David J. Glass,Justin R. Fallon,Edward G. Stopa,Edward G. Stopa +8 more
TL;DR: Examining the distribution of agrin and laminin within the VBM, and measuring the agrin concentration within hippocampus and prefrontal cortex, suggest that agrin is an important VBM-associated HSPG in the brain and that Agrin levels are altered in association with microvascular damage in AD.
Journal ArticleDOI
Dorsomedial SCN neuronal subpopulations subserve different functions in human dementia
David G. Harper,Edward G. Stopa,V. Kuo-LeBlanc,Ann C. McKee,Kentaro Asayama,Ladislav Volicer,Neil W. Kowall,Andrew Satlin +7 more
TL;DR: Evidence that the SCN is necessary for the maintenance of the circadian rhythm in humans, information on the role of neuronal subpopulations in subserving this function and the utility of dementia in elaborating brain-behaviour relationships in the human are provided.
Journal ArticleDOI
Human choroid plexus growth factors: What are the implications for CSF dynamics in Alzheimer's disease?
Edward G. Stopa,Tyler M. Berzin,Sunyoung Kim,Phillip C. Song,V. Kuo-LeBlanc,Monica Rodriguez-Wolf,Andrew Baird,Conrad E. Johanson +7 more
TL;DR: The presence of FGF and VEGF within the normal and AD choroid plexus is confirmed and the alteration of growth factors and their receptors may contribute to the pathogenesis of the hydrocephalus ex vacuo that is characteristically seen in AD.
Journal ArticleDOI
Effect of APOE genotype on microvascular basement membrane in Alzheimer's disease.
Stephen Salloway,Tamar L. Gur,Tyler M. Berzin,Brian D. Zipser,Stephen Correia,Virginia Hovanesian,Justin R. Fallon,V. Kuo-LeBlanc,David J. Glass,Christine M. Hulette,Carolyn Rosenberg,Michael P. Vitek,Edward G. Stopa +12 more
TL;DR: The hypothesis that APOE4,4 is associated with thinning of the microvascular basement membrane in Alzheimer's disease is supported.