V
Václav Janoušek
Researcher at Charles University in Prague
Publications - 24
Citations - 600
Václav Janoušek is an academic researcher from Charles University in Prague. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 12, co-authored 24 publications receiving 520 citations.
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Journal ArticleDOI
Genome-wide architecture of reproductive isolation in a naturally occurring hybrid zone between Mus musculus musculus and M. m. domesticus.
Václav Janoušek,Liuyang Wang,Ken Luzynski,Petra Dufková,Martina Vyskočilová,Michael W. Nachman,Pavel Munclinger,Miloš Macholán,Jaroslav Piálek,Priscilla K. Tucker +9 more
TL;DR: Results indicate that speciation in two recently diverged house mouse subspecies is complex, involving many genes dispersed throughout the genome and associated with distinct functions, and suggests a key role for several mechanisms, including the regulation of transcription, sexual conflict and sexual selection operating at both the postmating prezyGotic and postzygotic stages of reproductive isolation.
Journal ArticleDOI
Repeat associated mechanisms of genome evolution and function revealed by the Mus caroli and Mus pahari genomes.
David Thybert,David Thybert,Maša Roller,Fabio C. P. Navarro,Ian T. Fiddes,Ian Streeter,Christine Feig,David Martín-Gálvez,Mikhail Kolmogorov,Václav Janoušek,Wasiu Akanni,Bronwen Aken,Sarah Aldridge,Sarah Aldridge,Varshith Chakrapani,William Chow,Laura Clarke,Carla Cummins,Anthony G. Doran,Matthew Dunn,Leo Goodstadt,Kerstin Howe,Matthew Howell,Ambre Aurore Josselin,Robert C. Karn,Christina M. Laukaitis,Lilue Jingtao,Fergal J. Martin,Matthieu Muffato,Stefanie Nachtweide,Michael A. Quail,Cristina Sisu,Mario Stanke,Klara Stefflova,Cock van Oosterhout,Frédéric Veyrunes,Ben J. Ward,Fengtang Yang,Golbahar Yazdanifar,Amonida Zadissa,David J. Adams,Alvis Brazma,Mark Gerstein,Benedict Paten,Son Pham,Thomas M. Keane,Thomas M. Keane,Duncan T. Odom,Duncan T. Odom,Paul Flicek,Paul Flicek +50 more
TL;DR: In this article, the authors compared the evolutionary dynamics between the Muridae and Hominidae and found that the divergence times between the two families are similar in divergence times to each other, and that the relative rates of nucleotide change and feature turnover in both neutral and functional sequences of the two groups are similar.
Journal ArticleDOI
Measures of linkage disequilibrium among neighbouring SNPs indicate asymmetries across the house mouse hybrid zone
Liuyang Wang,Ken Luzynski,John E. Pool,Václav Janoušek,Petra Dufková,Martina Vyskočilová,Katherine C. Teeter,Michael W. Nachman,Pavel Munclinger,Miloš Macholán,Jaroslav Piálek,Priscilla K. Tucker +11 more
TL;DR: Empirical measures of LD provide evidence for extinction and (re)colonization in single populations and, together with simulations, suggest hybrid zone movement because of either geography‐dependent asymmetrical dispersal or selection favouring one subspecies over the other.
Journal ArticleDOI
Functional Organization of the Genome May Shape the Species Boundary in the House Mouse
TL;DR: Genomic characteristics of the species boundaries between two house mouse subspecies and a striking functional polarization of genes based on where they are expressed in the cell are examined, hypothesizing that functional organization of the genome is an important driver of species divergence.