V
Vahab Ali
Researcher at Rajendra Memorial Research Institute of Medical Sciences
Publications - 66
Citations - 1824
Vahab Ali is an academic researcher from Rajendra Memorial Research Institute of Medical Sciences. The author has contributed to research in topics: Entamoeba histolytica & Leishmania donovani. The author has an hindex of 22, co-authored 65 publications receiving 1610 citations. Previous affiliations of Vahab Ali include Central Drug Research Institute & National Institutes of Health.
Papers
More filters
Journal ArticleDOI
Current Therapeutics, Their Problems, and Sulfur-Containing-Amino-Acid Metabolism as a Novel Target against Infections by “Amitochondriate” Protozoan Parasites
Vahab Ali,Tomoyoshi Nozaki +1 more
TL;DR: The biology of these microaerophilic parasites, their clinical manifestation and epidemiology of disease, chemotherapeutics, the modes of action of representative drugs, and problems related to these drugs, including drug resistance are summarized.
Journal ArticleDOI
A Retromerlike Complex Is a Novel Rab7 Effector That Is Involved in the Transport of the Virulence Factor Cysteine Protease in the Enteric Protozoan Parasite Entamoeba histolytica
TL;DR: It is demonstrated that transport of CP is regulated through a specific interaction of Rab7A small GTPase (EhRab7A) with the retromerlike complex, consistent with the premise that the retRomerlikecomplex is involved in the retrograde transport of putative hydrolase receptor(s) from preparatory vacuoles and phagosomes to the Golgi apparatus.
Journal ArticleDOI
An Intestinal Parasitic Protist, Entamoeba histolytica, Possesses a Non-redundant Nitrogen Fixation-like System for Iron-Sulfur Cluster Assembly under Anaerobic Conditions
TL;DR: In this article, the authors characterized the Fe-S cluster formation in an anaerobic amitochondrial protozoan parasite, Entamoeba histolytica, in which FeS proteins play an important role in energy metabolism and electron transfer.
Journal ArticleDOI
8-anilino-1-naphthalene sulfonic acid (ANS) induces folding of acid unfolded cytochrome c to molten globule state as a result of electrostatic interactions.
TL;DR: This is the first experimental demonstration of ANS induced folding of unfolded protein and puts to question the usefulness of ANs for characterization/determination of partially folded intermediates of proteins observed under low pH conditions.
Book ChapterDOI
[Sulfur-containing amino acid metabolism in parasitic protozoa].
TL;DR: These pathways also demonstrate notable heterogeneity among parasites, suggesting that the metabolism of sulfur-containing amino acids reflects the diversity of parasitism among parasite species, and probably influences their biology and pathophysiology such as virulence competence and stress defense.