V
Valentina Oliveri
Researcher at University of Catania
Publications - 52
Citations - 1197
Valentina Oliveri is an academic researcher from University of Catania. The author has contributed to research in topics: Protein aggregation & Cyclodextrin. The author has an hindex of 18, co-authored 49 publications receiving 969 citations. Previous affiliations of Valentina Oliveri include University of Sussex.
Papers
More filters
Journal ArticleDOI
8-Hydroxyquinolines in medicinal chemistry: A structural perspective.
TL;DR: This review has summarized 8-Hydroxyquinolines, 8-hydroxyquinoline-like compounds,8-hydrox Quinoline-loaded nanoparticle systems with respect to their biological activities, interaction with metal ions and mechanisms of action.
Journal ArticleDOI
Gluconjugates of 8-hydroxyquinolines as potential anti-cancer prodrugs
TL;DR: It is demonstrated that glycoconjugates are cleaved in vitro by β-glucosidase and these systems exhibit antiproliferative activity against different tumor cell lines in the presence of copper(II) ions.
Journal ArticleDOI
Cyclodextrin Anchoring on Magnetic Fe3O4 Nanoparticles Modified with Phosphonic Linkers
Cristina Tudisco,Valentina Oliveri,Maria Cantarella,Graziella Vecchio,Guglielmo G. Condorelli +4 more
TL;DR: The ability of β-CD-functionalized nanoparticles to carry and slowly release some drugs has been tested by adopting the anti-inflammatory drug diclofenac sodium salt as a model.
Journal ArticleDOI
New cyclodextrin-bearing 8-hydroxyquinoline ligands as multifunctional molecules
Valentina Oliveri,Valentina Oliveri,Antonino Puglisi,Maurizio Viale,Cinzia Aiello,Carmelo Sgarlata,Graziella Vecchio,James Clarke,John Milton,John Spencer +9 more
TL;DR: Three new β-cyclodextrin conjugates of 8-hydroxyquinolines and their copper( II) and zinc(II) complexes have been synthesized and characterized spectroscopically, and show low cytotoxicity and potential as therapeutic agents in diseases related both to metal dyshomeostasis and oxidative stress.
Journal ArticleDOI
Glycosylated copper(II) ionophores as prodrugs for β-glucosidase activation in targeted cancer therapy
Valentina Oliveri,Maurizio Viale,Giulia Caron,Cinzia Aiello,Rosaria Gangemi,Graziella Vecchio +5 more
TL;DR: In vitro data show that 2 out of 3 glycosylated compounds possess a pharmacologically-relevant antiproliferative activity against tumor cells, similar to that of their parent compounds; this activity is associated with a relevant triggering of apoptosis.