V
Venkata Ramesh Dasari
Researcher at Geisinger Medical Center
Publications - 8
Citations - 111
Venkata Ramesh Dasari is an academic researcher from Geisinger Medical Center. The author has contributed to research in topics: Exome sequencing & Cancer. The author has an hindex of 3, co-authored 8 publications receiving 86 citations.
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Verteporfin exhibits YAP-independent anti-proliferative and cytotoxic effects in endometrial cancer cells.
TL;DR: The results suggest that VP is a promising chemotherapeutic agent for the treatment of endometrial cancer.
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Exome-Wide Rare Variant Analysis From the DiscovEHR Study Identifies Novel Candidate Predisposition Genes for Endometrial Cancer.
TL;DR: Exome-wide rare variant association using single-source electronic health records linked to genomic data highlights candidate genes and pathways associated with endometrial cancer and indicates rare variants involvement in endometricrial cancer predisposition, which could help in personalized prognosis and also further the understanding of its genetic etiology.
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Differential gene expression induced by Verteporfin in endometrial cancer cells.
TL;DR: RNA sequencing data revealed multiple key genes of pathological significance in EMCA, thereby improving the understanding of molecular profiles of EMCA cells and indicating that subcutaneous tumors in mice were regressed after VP treatment by inhibiting cell cycle pathway proteins.
Journal ArticleDOI
Synergistic enhancement of efficacy of platinum drugs with verteporfin in ovarian cancer cells
TL;DR: The results suggest that novel combinations of VP with CDDP or CP or Taxol might be an attractive therapeutic strategy to enhance OVCA chemosensitivity and lead to the development of an innovative combination therapy for the treatment of OV CA patients.
Journal ArticleDOI
Systematic characterization of germline variants from the DiscovEHR study endometrial carcinoma population.
Jason E. Miller,Raghu Metpally,Thomas N. Person,Sarathbabu Krishnamurthy,Venkata Ramesh Dasari,Manu Shivakumar,Daniel R. Lavage,Adam M. Cook,David J. Carey,Marylyn D. Ritchie,Dokyoon Kim,Radhika Gogoi +11 more
TL;DR: This systematic characterization of potentially pathogenic germline variants describes the genetic underpinnings of EMCA through the use of data from a single hospital system.