Vera Neves

TL;DR: This work presents a method for the triple functionalisation of oxidised SWCNTs with the anti-cancer drug doxorubicin, a monoclonal antibody, and a fluorescent marker at non-competing binding sites, and shows that the complex is efficiently taken up by cancer cells with subsequent intracellular release of doxorbicin.

TL;DR: Investigations indicate that both CNT dimensions and surface functionalization have a significant influence on their dispersion and in vitro behavior, and factors such as a short aspect ratio, presence of oxidation debris and serum proteins, low salt concentration, and an appropriate pH are shown to improve the dispersion stability.

TL;DR: A drug delivery system for the anti-cancer drugs doxorubicin and mitoxantrone based on carbon nanotubes is designed, which is stable under biological conditions, allows for sustained release, and promotes selectivity through an active targeting scheme.

TL;DR: It is demonstrated that an oral vaccine based on live recombinant Lactobacillus plantarum protects mice from tick-transmitted Borrelia burgdorferi infection and can be applied to design oral vaccine delivery vehicles against several microbial pathogens.

TL;DR: Advances in the development and engineering of therapeutic BBB-crossing antibodies and their high potential for treatment of CNS disorders are reviewed.