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Vera Saldien

Researcher at University of Antwerp

Publications -  50
Citations -  1366

Vera Saldien is an academic researcher from University of Antwerp. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 15, co-authored 38 publications receiving 1167 citations.

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Early reversal of profound rocuronium-induced neuromuscular blockade by sugammadex in a randomized multicenter study - Efficacy, safety, and pharmacokinetics

TL;DR: In male subjects, sugammadex safely reversed profound neuromuscular blockade induced by 0.6 mg/kg rocuronium in a dose-dependent manner and enhanced the renal excretion of rocur onium, and its clearance is approximately one third that of roCuronium.
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Drug-induced sleep endoscopy in sleep-disordered breathing: report on 1,249 cases.

TL;DR: Upper airway collapse patterns during drug‐induced sleep endoscopy (DISE) in a large cohort of patients with sleep‐disordered breathing and to assess associations with anthropometric and polysomnographic parameters are described.
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Reversal of rocuronium-induced neuromuscular block with the novel drug sugammadex is equally effective under maintenance anesthesia with propofol or sevoflurane.

TL;DR: The 95% confidence interval for the difference in recovery time between the 2 groups was well within the predefined equivalence interval, indicating that recovery from NMB was unaffected by maintenance anesthesia, and the safety profile of sugammadex was somewhat more favorable under propofol than under sevoflurane anesthesia.
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Sleep endoscopy with simulation bite for prediction of oral appliance treatment outcome

TL;DR: The results of this study suggest that the use of a simulation bite in maximal comfortable protrusion of the mandible, as used during DISE in patients with OSA, tends to be effective in predicting treatment response of MAD treatment.
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A randomized, dose-response study of sugammadex given for the reversal of deep rocuronium- or vecuronium-induced neuromuscular blockade under sevoflurane anesthesia.

TL;DR: A dose-response effect was demonstrated for decreased mean time to recovery of the T4/T1 ratio to 0.9 with increasing sugammadex dose in both NMBD groups (per-protocol population): rocuronium group and 47 in the vecur onium group.