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Verena Coleman

Researcher at University of Potsdam

Publications -  9
Citations -  316

Verena Coleman is an academic researcher from University of Potsdam. The author has contributed to research in topics: FGF21 & Myokine. The author has an hindex of 7, co-authored 9 publications receiving 206 citations.

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Regulation of myokine expression: Role of exercise and cellular stress.

TL;DR: Recent technological advances have led to the identification of numerous potential new myokines but for most of them regulation by oxidative and ER-stress still needs to be unraveled.
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Muscle mitochondrial stress adaptation operates independently of endogenous FGF21 action

TL;DR: It is found that FGF21 played a negligible role in muscle mitochondrial stress-related improved obesity resistance, glycemic control and hepatic lipid homeostasis, and the protective cell-autonomous muscle mitohormesis and metabolic stress adaptation did not require the presence of FGF 21.
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Muscle-derived GDF15 drives diurnal anorexia and systemic metabolic remodeling during mitochondrial stress.

TL;DR: Evidence suggests a novel diurnal action and key pathophysiological role of mitochondrial stress‐induced GDF15 in the regulation of systemic energy metabolism and genetic loss in UCP1‐TG mice promotes a progressive increase in body fat mass.
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Partial involvement of Nrf2 in skeletal muscle mitohormesis as an adaptive response to mitochondrial uncoupling.

TL;DR: Results tune down the functions controlled by Nrf2 in muscle mitohormesis and oxidative stress defense during mitochondrial OXPHOS inefficiency.