V
Verônica Santana de Freitas-Blanco
Researcher at State University of Campinas
Publications - 8
Citations - 241
Verônica Santana de Freitas-Blanco is an academic researcher from State University of Campinas. The author has contributed to research in topics: Spilanthol & Acmella oleracea. The author has an hindex of 6, co-authored 8 publications receiving 169 citations. Previous affiliations of Verônica Santana de Freitas-Blanco include University of Southern California.
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Candida albicans stimulates Streptococcus mutans microcolony development via cross-kingdom biofilm-derived metabolites.
Dongyeop Kim,Arjun Sengupta,Tagbo H.R. Niepa,Byung-Hoo Lee,Aalim M. Weljie,Verônica Santana de Freitas-Blanco,Ramiro Mendonça Murata,Kathleen J. Stebe,Daeyeon Lee,Hyun Koo +9 more
TL;DR: The data revealed that bacterial-fungal derived conditioned medium (BF-CM) significantly increased the growth of S. mutans and altered biofilm 3D-architecture in a dose-dependent manner, resulting in enlarged and densely packed bacterial cell-clusters (microcolonies).
Journal ArticleDOI
Development and Evaluation of a Novel Mucoadhesive Film Containing Acmella oleracea Extract for Oral Mucosa Topical Anesthesia.
Verônica Santana de Freitas-Blanco,Michelle Franz-Montan,Francisco Carlos Groppo,João Carvalho,Glyn Mara Figueira,Luciano Serpe,Ilza Maria de Oliveira Sousa,Viviane Aparecida Guilherme Damasio,Lais Thiemi Yamane,Eneida de Paula,Rodney Alexandre Ferreira Rodrigues +10 more
TL;DR: Mucoadhesive film containing crude extract of jambu treated with activated carbon is a potential alternative for oral, topical use, encouraging future clinical studies.
Journal ArticleDOI
Acmella oleracea and Achyrocline satureioides as Sources of Natural Products in Topical Wound Care
Lais Thiemi Yamane,Eneida de Paula,Michelle Pedroza Jorge,Verônica Santana de Freitas-Blanco,Ílio Montanari Junior,Glyn Mara Figueira,Luís Adriano Anholeto,Patrícia Rosa de Oliveira,Rodney Alexandre Ferreira Rodrigues +8 more
TL;DR: The results demonstrate that the native species from Brazil with a huge therapeutic potential, with proved anti-inflammatory and anesthetic action, have a potential use in skin wounds, pressure sore, and infected surgical wounds treatment.
Journal ArticleDOI
Spilanthol, the Principal Alkylamide from Acmella oleracea, Attenuates 5-Fluorouracil-Induced Intestinal Mucositis in Mice.
Verônica Santana de Freitas-Blanco,Karin Maia Monteiro,Patrícia Rosa de Oliveira,Ellen C.S. de Oliveira,Lucia Elaine de Oliveira Braga,João Carvalho,Rodney Alexandre Ferreira Rodrigues +6 more
TL;DR: It is demonstrated that spilanthol effectively reduced inflammation in a mouse model of intestinal mucositis induced by 5-FU, and that the compound might be a promising therapeutic candidate for the prevention and treatment of this condition.
Journal ArticleDOI
A new approach for the total synthesis of spilanthol and analogue with improved anesthetic activity
Isabella Gonçalves Alonso,Lais Thiemi Yamane,Verônica Santana de Freitas-Blanco,Luiz F. T. Novaes,Michelle Franz-Montan,Eneida de Paula,Marili V.N. Rodrigues,Rodney Alexandre Ferreira Rodrigues,Julio Cezar Pastre +8 more
TL;DR: In this article, a 5-step synthesis of spilanthol (affinin) is reported, where the route features complete control of alkene geometry during the assembling of the double bonds, with the use of a Sonogashira cross-coupling reaction, a Z-selective alkyne semi-reduction and a HWE olefination reaction as the key steps.