Veselin Mitrovic

TL;DR: Although the primary end point of the study was not met, riociguat was well tolerated in patients with pulmonary hypertension caused by systolic left ventricular dysfunction and improved cardiac index and pulmonary and systemic vascular resistance.

TL;DR: Neurohumoral activation as evidenced by NT-proBNP appears as a unifying feature that is independent of other biochemical markers (myocardial necrosis, inflammation) and is a powerful and independent determinant of the short-term cardiac risk in patients with acute coronary syndromes.

TL;DR: In a contemporary AF population, LA structure and function were increasingly abnormal with a greater electrical burden of AF and higher stroke risk estimated by the CHADS2 score, suggesting that the assessment of LA function may add important incremental information in the evaluation of AF patients.

TL;DR: Ularitide lowered cardiac filling pressures and improved dyspnoea without apparent early deleterious effects on renal function in DHF patients, suggesting that ularitides may play a role in the management of DHF.

TL;DR: NT-proBNP is elevated in patients with stable angina pectoris and has a close correlation to disease severity, and combined with exercise testing, the test accuracy for predicting severe CAD can be improved.