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Amil M. Shah
Researcher at Brigham and Women's Hospital
Publications - 325
Citations - 16392
Amil M. Shah is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Heart failure & Ejection fraction. The author has an hindex of 55, co-authored 247 publications receiving 11979 citations. Previous affiliations of Amil M. Shah include Veterans Health Administration & Mackay Memorial Hospital.
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Journal ArticleDOI
The angiotensin receptor neprilysin inhibitor LCZ696 in heart failure with preserved ejection fraction: A phase 2 double-blind randomised controlled trial
Scott D. Solomon,Michael R. Zile,Burkert Pieske,Adriaan A. Voors,Amil M. Shah,Elisabeth Kraigher-Krainer,Victor Shi,Toni Bransford,Madoka Takeuchi,Jianjian Gong,Martin Lefkowitz,Milton Packer,John J.V. McMurray +12 more
TL;DR: In patients with heart failure with preserved ejection fraction, LCZ696 reduced NT-proBNP to a greater extent than did valsartan at 12 weeks and was well tolerated; whether these effects would translate into improved outcomes needs to be tested prospectively.
Journal ArticleDOI
Inotersen Treatment for Patients with Hereditary Transthyretin Amyloidosis
Merrill D. Benson,Márcia Waddington-Cruz,John L. Berk,Michael Polydefkis,Peter J. Dyck,Annabel K. Wang,Violaine Planté-Bordeneuve,Fabio Barroso,Giampaolo Merlini,Laura Obici,Morton A. Scheinberg,Thomas H. Brannagan,William J. Litchy,Carol J. Whelan,Brian M. Drachman,David C. Adams,Stephen B. Heitner,Isabel Conceição,Hartmut H. Schmidt,Giuseppe Vita,Josep M. Campistol,Josep Gamez,Peter D. Gorevic,Edward Gane,Amil M. Shah,Scott D. Solomon,Brett P. Monia,Steven G. Hughes,Jesse Kwoh,Bradley W. McEvoy,Shiangtung W. Jung,Brenda F. Baker,Elizabeth J. Ackermann,Morie A. Gertz,Teresa Coelho +34 more
TL;DR: Inotersen improved the course of neurologic disease and quality of life in patients with hereditary transthyretin amyloidosis and improvements were independent of disease stage, mutation type, or the presence of cardiomyopathy.
Journal ArticleDOI
Vitamin D levels and early mortality among incident hemodialysis patients.
Myles Wolf,Amil M. Shah,Orlando M. Gutiérrez,Elizabeth Ankers,M. Monroy,Hector Tamez,David J.R. Steele,Yuchiao Chang,Carlos A. Camargo,Marcello Tonelli,Ravi Thadhani +10 more
TL;DR: This study shows that among incident hemodialysis patients, vitamin D deficiency is common, correlates poorly with other components of mineral metabolism and is associated with increased early mortality.
Journal ArticleDOI
Impaired Systolic Function by Strain Imaging in Heart Failure With Preserved Ejection Fraction
Elisabeth Kraigher-Krainer,Amil M. Shah,Deepak K. Gupta,Angela B. S. Santos,Brian Claggett,Burkert Pieske,Michael R. Zile,Adriaan A. Voors,Martin Lefkowitz,Milton Packer,John J.V. McMurray,Scott D. Solomon +11 more
TL;DR: Strain imaging detects impaired systolic function despite preserved global LVEF inHFpEF that may contribute to the pathophysiology of the HFpEF syndrome.
Journal ArticleDOI
Dietary carbohydrate intake and mortality: a prospective cohort study and meta-analysis.
Sara B. Seidelmann,Brian Claggett,Susan Cheng,Mir Henglin,Amil M. Shah,Lyn M. Steffen,Aaron R. Folsom,Eric B. Rimm,Eric B. Rimm,Walter C. Willett,Walter C. Willett,Scott D. Solomon +11 more
TL;DR: Both high and low percentages of carbohydrate diets were associated with increased mortality, with minimal risk observed at 50–55% carbohydrate intake, and it is suggested that the source of food notably modifies the association between carbohydrate intake and mortality.