V
Vincent C. Hascall
Researcher at Cleveland Clinic
Publications - 206
Citations - 13815
Vincent C. Hascall is an academic researcher from Cleveland Clinic. The author has contributed to research in topics: Hyaluronic acid & Proteoglycan. The author has an hindex of 64, co-authored 193 publications receiving 12685 citations. Previous affiliations of Vincent C. Hascall include Abbott Northwestern Hospital & Shriners Hospitals for Children.
Papers
More filters
Journal ArticleDOI
Hyperglycemia diverts dividing stem cells to pathological adipogenesis.
Vincent C. Hascall,Aimin Wang +1 more
TL;DR: This commentary proposes a mechanism for why murine diabetic adipose tissue contains very few remaining stem cells compared with normal adipose tissues, and involves the diversion of stem cells to pathological adipocytes when they divide in hyperglycemia.
Journal ArticleDOI
Irreversible heavy chain transfer to chondroitin.
TL;DR: The interpretation is that TSG-6 swaps the HCs from the larger, reversible sites on chondroitin chains, which function as HC acceptors, onto smaller chondDetroitin chains that function as irreversible HC acceptor.
Journal ArticleDOI
Proteomic, Mechanical, and Biochemical Characterization of Cartilage Development.
Benjamin J. Bielajew,Ryan P. Donahue,Elliott K. Lamkin,Jerry C. Hu,Vincent C. Hascall,Kyriacos A. Athanasiou +5 more
TL;DR: In this paper , the development of porcine articular cartilage is examined through biomechanical, biochemical, and proteomic techniques, to determine how mechanics and extracellular matrix composition change from fetal to mature cartilage.
Journal ArticleDOI
Periostin/Filamin-A: A Candidate Central Regulatory Axis for Valve Fibrogenesis and Matrix Compaction.
Suniti Misra,Shibnath Ghatak,Ricardo A. Moreno-Rodriguez,Russell A. Norris,Vincent C. Hascall,Roger R. Markwald +5 more
TL;DR: In this article, the authors examined whether filamin-A has a cross-talk with periostin/signaling that promotes remodeling of postnatal heart valves into mature-leaflets.
Journal ArticleDOI
Role of FGF and Hyaluronan in Choroidal Neovascularization in Sorsby Fundus Dystrophy.
Alyson Wolk,Alyson Wolk,Dilara Hatipoglu,Alecia Cutler,Mariya Ali,Lestella Bell,Lestella Bell,Jian Hua Qi,Rupesh Singh,Julia C Batoki,Laura Karle,Vera L. Bonilha,Vera L. Bonilha,Oliver Wessely,Oliver Wessely,Heidi Stoehr,Vincent C. Hascall,Bela Anand-Apte,Bela Anand-Apte +18 more
TL;DR: It is demonstrated that hyaluronan (HA), a large glycosaminoglycan, is elevated in the plasma and retinal pigment epithelium (RPE)/choroid of patients with AMD and the TIMP3-MMP-FGF-2-HA axis may have an important role in the pathogenesis of CNV in SFD.