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Vincenzo C. Russo

Researcher at Royal Children's Hospital

Publications -  57
Citations -  2702

Vincenzo C. Russo is an academic researcher from Royal Children's Hospital. The author has contributed to research in topics: Growth factor & Insulin-like growth factor-binding protein. The author has an hindex of 29, co-authored 57 publications receiving 2529 citations. Previous affiliations of Vincenzo C. Russo include University of Melbourne.

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Effects of fluctuating glucose levels on neuronal cells in vitro.

TL;DR: Both treatments showed that fluctuating osmolality did not result in a significant change in mitochondrial activity and had no effects on 14Cglucose uptake, suggesting that adverse effects on mitochondrial function were specifically related to metabolically active glucose fluctuations.
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Physiology and pathophysiology of IGFBP-1 and IGFBP-2 - consensus and dissent on metabolic control and malignant potential.

TL;DR: A relationship between IGFBP-2 and breast cancer, ovarian cancer and prostate cancer does indeed appear to be present, and there is accumulating evidence for an effect of IGF BP-2 on PI3K signalling via PTEN, particularly in breast cancer.
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Interactions between bcl-2 and the IGF system control apoptosis in the developing mouse brain.

TL;DR: These studies indicate that in the developing brain IGF-I modulates expression of its major binding protein IGFBP-2, as well as the Bcl-2 protein, which is likely to provide a robust system of cell protection during brain development and repair.