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Vladimir Badmaev

Researcher at City University of New York

Publications -  41
Citations -  1771

Vladimir Badmaev is an academic researcher from City University of New York. The author has contributed to research in topics: Pterostilbene & Vitamin D and neurology. The author has an hindex of 20, co-authored 41 publications receiving 1579 citations.

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Inhibitory activity of boswellic acids from Boswellia serrata against human leukemia HL-60 cells in culture

TL;DR: Four major triterpene acids, isolated from the gum resin of Boswellia serrata, inhibited the synthesis of DNA, RNA and protein in human leukemia HL-60 cells in a dose dependent manner and the effect of 4 on DNA synthesis was found to be irreversible.
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Increased growth inhibitory effects on human cancer cells and anti-inflammatory potency of shogaols from Zingiber officinale relative to gingerols.

TL;DR: The results showed that shogaols had much stronger growth inhibitory effects than gingerols on H-1299 human lung cancer cells and HCT-116 human colon cancer cells, especially when comparing [ 6]-shogaol with [6]-gingerol (IC50 of approximately 8 versus approximately 150 microM).
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Pterostilbene induces apoptosis and cell cycle arrest in human gastric carcinoma cells.

TL;DR: In this article, the effects of pterostilbene on cell viability in human gastric carcinoma AGS cells were investigated and it was shown that pterobox was able to inhibit cell proliferation and induce apoptosis in a concentration-and time-dependent manner.
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Tetrahydrocurcumin, a major metabolite of curcumin, induced autophagic cell death through coordinative modulation of PI3K/Akt-mTOR and MAPK signaling pathways in human leukemia HL-60 cells.

TL;DR: Treatment with THC induced autophagic cell death in human HL-60 promyelocytic leukemia cells by increasing autophage marker acidic vascular organelle (AVO) formation and demonstrated the anticancer efficacy of THC by inducing autophagy as well as provided a potential application for the prevention of human leukemia.