W
W. Weyenberg
Researcher at University of Antwerp
Publications - 27
Citations - 867
W. Weyenberg is an academic researcher from University of Antwerp. The author has contributed to research in topics: PLGA & Zeta potential. The author has an hindex of 14, co-authored 27 publications receiving 799 citations.
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Journal ArticleDOI
Mucoadhesive ocular insert based on thiolated poly(acrylic acid): development and in vivo evaluation in humans.
TL;DR: The in vivo study showed that ocular inserts based on thiolated poly(acrylic acid) are promising new solid devices for ocular drug delivery, whereas the fluorescein concentration rapidly decreased after application of aqueous eye drops or insertsbased on unmodified poly(Acrylic acid).
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PLGA nanoparticles and nanosuspensions with amphotericin B : potent **in vitro** and **in vivo** alternatives to Fungizone® and AmBisome®
H. Van de Ven,Caroline Paulussen,Pim-Bart Feijens,A. Matheeussen,Patrick Rombaut,Pieterjan Kayaert,G. Van den Mooter,W. Weyenberg,Paul Cos,Louis Maes,Annick Ludwig +10 more
TL;DR: It is demonstrated that the superior in vitro antifungal activity could be extrapolated to the in vivo situation and the developed AmB nanomedicines could represent potent and cost-effective alternatives to Fungizone and AmBisome.
Journal ArticleDOI
Cytotoxicity of submicron emulsions and solid lipid nanoparticles for dermal application
W. Weyenberg,Plamen Filev,Dave Van den Plas,Jo Vandervoort,Kris De Smet,Philippe Sollie,Annick Ludwig +6 more
TL;DR: The cytotoxicity and physical properties of various submicron O/W emulsions and solid lipid nanoparticles for dermal applications were investigated and survival of macrophages was highly affected by stearic acid and stearylamine.
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Development and characterization of mucoadhesive chitosan films for ophthalmic delivery of cyclosporine A
Kris Hermans,Dave Van den Plas,Sabina Kerimova,Robert Carleer,Peter Adriaensens,W. Weyenberg,Annick Ludwig +6 more
TL;DR: None of the film formulations showed significant cytotoxicity as compared to the negative control using human epithelial cells (HaCaT).
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PLGA nanoparticles loaded with the antileishmanial saponin β-aescin: factor influence study and in vitro efficacy evaluation.
H. Van de Ven,Marieke Vermeersch,A. Matheeussen,Jo Vandervoort,W. Weyenberg,Sandra Apers,Paul Cos,Louis Maes,Annick Ludwig +8 more
TL;DR: The in vitro results confirmed the hypothesis that poly(d,l-lactide-co-glycolide) nanoparticles (NPs) for the antileishmanial saponin β-aescin confirmed the therapeutic index of the conventional drugs in the treatment of visceral leishmaniasis.