Optical coherence tomography angiography.

Optical coherence tomography angiography: A comprehensive review of current methods and clinical applications.

We propose an asymmetric cryptosystem based on a phase-truncated Fourier transform. With phase truncation in Fourier transform, one is able to produce an asymmetric ciphertext as real-valued and stationary white noise by using two random phase keys as public keys, while a legal user can retrieve the plaintext using another two different private phase keys in the decryption process. Owing to the nonlinear operation of phase truncation, high robustness against existing attacks could be achieved. A set of simulation results shows the validity of proposed asymmetric cryptosystem.

Asymmetric cryptosystem based on phase-truncated Fourier transforms.

The ability to dynamically image features deep within living organisms, permitting real-time analysis of cellular structure and function, is important for biological science. This Review article discusses multiphoton microscopy capable of such analysis, along with technologies that are pushing the limits of phenomena that can be quantitatively imaged.

/pdf/advances-in-multiphoton-microscopy-technology-42gqk18ef1.pdf

Advances in multiphoton microscopy technology

Information security with optical means, such as double random phase encoding, has been investigated by various researchers. It has been demonstrated that optical technology possesses several unique characteristics for securing information compared with its electronic counterpart, such as many degrees of freedom. In this paper, we present a review of optical technologies for information security. Optical security systems are reviewed, and theoretical principles and implementation examples are presented to illustrate each optical security system. In addition, advantages and potential weaknesses of each optical security system are analyzed and discussed. It is expected that this review not only will provide a clear picture about current developments in optical security systems but also may shed some light on future developments.

Advances in optical security systems

Vascularization and efficient perfusion are long-standing challenges in cardiac tissue engineering. Here we report engineered perfusable microvascular constructs, wherein human embryonic stem cell-derived endothelial cells (hESC-ECs) are seeded both into patterned microchannels and the surrounding collagen matrix. In vitro, the hESC-ECs lining the luminal walls readily sprout and anastomose with de novo-formed endothelial tubes in the matrix under flow. When implanted on infarcted rat hearts, the perfusable microvessel grafts integrate with coronary vasculature to a greater degree than non-perfusable self-assembled constructs at 5 days post-implantation. Optical microangiography imaging reveal that perfusable grafts have 6-fold greater vascular density, 2.5-fold higher vascular velocities and >20-fold higher volumetric perfusion rates. Implantation of perfusable grafts containing additional hESC-derived cardiomyocytes show higher cardiomyocyte and vascular density. Thus, pre-patterned vascular networks enhance vascular remodeling and accelerate coronary perfusion, potentially supporting cardiac tissues after implantation. These findings should facilitate the next generation of cardiac tissue engineering design.

/pdf/patterned-human-microvascular-grafts-enable-rapid-3uw49irmz2.pdf

Patterned human microvascular grafts enable rapid vascularization and increase perfusion in infarcted rat hearts.

From the perspective of optical information security, we demonstrate that conventional phase retrieval algorithms, such as the Gerchberg–Saxton algorithm, can be still valid when extended from the Fourier transform domain into the fractional Fourier transform (FRFT) domain. Based on this extension, we propose a method of known-plaintext attack (KPA) on double random phase encoding in the fractional Fourier transform domain (DRPE-FRFT). With this attack, an opponent can access two encryption phase keys with the help of the phase retrieval algorithm in the FRFT domain, and meanwhile obtain the two FRFT order keys by using an exhaustive search. This indicates that the optical encryption scheme based on the DRPE-FRFT scheme is vulnerable to KPA due to the nature of the linearity of FRFT. The validity of this attack is verified by numerical simulations.

http://iopscience.iop.org/article/10.1088/1464-4258/11/7/075402/pdf

Vulnerability to known-plaintext attack of optical encryption schemes based on two fractional Fourier transform order keys and double random phase keys

We demonstrate the use of an ultra-high-speed swept-source optical coherence tomography (OCT) to achieve optical micro-angiography (OMAG) of microcirculatory tissue beds in vivo. The system is based on a 1310-nm Fourier domain mode-locking (FDML) laser with 1.6-MHz A-line rate, providing a frame rate of 3.415 KHz, an axial resolution of ∼10  μm and signal to noise ratio of 102 dB. Motion from blood flow causes change in OCT signals between consecutive B-frames acquired at the same location. Intensity-based inter-frame subtraction algorithm is applied to extract blood flow from tissue background without any motion correction. We demonstrate the capability of this 1.6-MHz OCT system for 4D OMAG of in vivo tissue at a volume rate of 4.7 volumes/s (volume size: 512×200×720 voxels).

/pdf/4d-optical-coherence-tomography-based-micro-angiography-8ipqu09h41.pdf

4D optical coherence tomography-based micro-angiography achieved by 1.6-MHz FDML swept source.

We propose a novel optical asymmetric cryptosystem based on a phase-truncated Fourier transform. Two decryption keys independent of each other are generated. They are referred to as universal key and special key, respectively. Each of them can be used for decryption independently in absence of the other. The universal key is applicable to decrypt any ciphertext encoded by the same encryption key, but with poor legibility. On the contrary, the special key is adequate for legible decryption, but only valid for one ciphertext corresponding to the specified plaintext. A set of simulation results show the interesting performance of two types of decryption keys.

https://www.spiedigitallibrary.org/journals/Optical-Engineering/volume-50/issue-8/080501/Universal-and-special-keys-based-on-phase-truncated-Fourier-transform/10.1117/1.3607421.pdf

Wan Qin

Papers

Asymmetric cryptosystem based on phase-truncated Fourier transforms.

Patterned human microvascular grafts enable rapid vascularization and increase perfusion in infarcted rat hearts.

Vulnerability to known-plaintext attack of optical encryption schemes based on two fractional Fourier transform order keys and double random phase keys

4D optical coherence tomography-based micro-angiography achieved by 1.6-MHz FDML swept source.

Universal and special keys based on phase-truncated Fourier transform.