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Wei Ren
Researcher at Hainan University
Publications - 24
Citations - 331
Wei Ren is an academic researcher from Hainan University. The author has contributed to research in topics: Aptamer & Dextranase. The author has an hindex of 8, co-authored 24 publications receiving 167 citations. Previous affiliations of Wei Ren include Dalian Ocean University & Nanjing Agricultural University.
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Journal ArticleDOI
The atmospheric and room-temperature plasma (ARTP) method on the dextranase activity and structure
TL;DR: Experiments performed in vitro suggested that this endo-dextranase may inhibit biofilm formation by Streptococcus mutans.
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Purification and Characterization of a Biofilm-Degradable Dextranase from a Marine Bacterium.
TL;DR: Cadex from a marine bacterium was shown to be an alkaline and cold-adapted endo-type dextranase suitable for development of a novel marine agent for the treatment of dental caries.
Journal ArticleDOI
Selection of a metal ligand modified DNAzyme for detecting Ni2.
Wei Ren,Po-Jung Jimmy Huang,Donatien de Rochambeau,Woohyun J. Moon,Jinyi Zhang,Mingsheng Lyu,Shujun Wang,Hanadi F. Sleiman,Juewen Liu +8 more
TL;DR: To increase Ni2+ binding, a glycyl-histidine-functionalized tertiary amine moiety was inserted at the cleavage junction and a catalytic beacon biosensor was designed by labeling a fluorophore and a quencher on the Ni03l DNAzyme.
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Selection of DNAzymes for Sensing Aquatic Bacteria: Vibrio Anguillarum.
TL;DR: Being the first work of DNAzyme-based sensing of aquatic bacteria, this study indicates that unmodified DNA can be used for targeting bacterial CEM, and it provides a new framework for developing other RNA-cleaving DNAzymes for rapid detection of pathogenic bacteria and water pollution.
Journal ArticleDOI
Crystal Structure of GH49 Dextranase from Arthrobacter oxidans KQ11: Identification of Catalytic Base and Improvement of Thermostability Using Semirational Design Based on B-Factors
Wei Ren,Le Liu,Lide Gu,Wanli Yan,Yan li Feng,Dongxue Dong,Shujun Wang,Mingsheng Lyu,Changhai Wang +8 more
TL;DR: The thermostability of the S357F mutant using semirational design based on B-factors was clearly better than that of wild-type Aodex, and this process may promote the aromatic-aromatic interactions that increase the thermostable of mutant Phe357.