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Shujun Wang
Researcher at Anhui University
Publications - 25
Citations - 391
Shujun Wang is an academic researcher from Anhui University. The author has contributed to research in topics: Dextranase & Aptamer. The author has an hindex of 8, co-authored 25 publications receiving 185 citations.
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Journal ArticleDOI
Research Progress on Rolling Circle Amplification (RCA)-Based Biomedical Sensing
TL;DR: In this review, improvements in using the RCA technique for medical biosensors and biomedical applications were summarized and future trends in related research fields described.
Journal ArticleDOI
DNAzyme biosensors for the detection of pathogenic bacteria
TL;DR: This review summarizes the current methods of detecting pathogenic bacteria based on various DNAzyme sensors and includes the design principles, working mechanisms, and detection applications of these sensors and discuss the experimental and theoretical bases for their application.
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Selection of a metal ligand modified DNAzyme for detecting Ni2.
Wei Ren,Po-Jung Jimmy Huang,Donatien de Rochambeau,Woohyun J. Moon,Jinyi Zhang,Mingsheng Lyu,Shujun Wang,Hanadi F. Sleiman,Juewen Liu +8 more
TL;DR: To increase Ni2+ binding, a glycyl-histidine-functionalized tertiary amine moiety was inserted at the cleavage junction and a catalytic beacon biosensor was designed by labeling a fluorophore and a quencher on the Ni03l DNAzyme.
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Selection of DNAzymes for Sensing Aquatic Bacteria: Vibrio Anguillarum.
TL;DR: Being the first work of DNAzyme-based sensing of aquatic bacteria, this study indicates that unmodified DNA can be used for targeting bacterial CEM, and it provides a new framework for developing other RNA-cleaving DNAzymes for rapid detection of pathogenic bacteria and water pollution.
Journal ArticleDOI
Crystal Structure of GH49 Dextranase from Arthrobacter oxidans KQ11: Identification of Catalytic Base and Improvement of Thermostability Using Semirational Design Based on B-Factors
Wei Ren,Le Liu,Lide Gu,Wanli Yan,Yan li Feng,Dongxue Dong,Shujun Wang,Mingsheng Lyu,Changhai Wang +8 more
TL;DR: The thermostability of the S357F mutant using semirational design based on B-factors was clearly better than that of wild-type Aodex, and this process may promote the aromatic-aromatic interactions that increase the thermostable of mutant Phe357.