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Wei Wang

Researcher at Beijing University of Chinese Medicine

Publications -  170
Citations -  4510

Wei Wang is an academic researcher from Beijing University of Chinese Medicine. The author has contributed to research in topics: Blood stasis & Heart failure. The author has an hindex of 27, co-authored 167 publications receiving 3102 citations. Previous affiliations of Wei Wang include Peking Union Medical College & Beijing Normal University.

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BATMAN-TCM: a Bioinformatics Analysis Tool for Molecular mechANism of Traditional Chinese Medicine

TL;DR: BATMAN-TCM will contribute to the understanding of the “multi-component, multi-target and multi-pathway” combinational therapeutic mechanism of TCM, and provide valuable clues for subsequent experimental validation, accelerating the elucidation of TCm’s molecular mechanism.
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A systematic prediction of multiple drug-target interactions from chemical, genomic, and pharmacological data.

TL;DR: This work reports a systematic approach that efficiently integrates the chemical, genomic, and pharmacological information for drug targeting and discovery on a large scale, based on two powerful methods of Random Forest and Support Vector Machine, and demonstrates the reliability and robustness of the obtained models.
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SymMap: an integrative database of traditional Chinese medicine enhanced by symptom mapping.

TL;DR: SymMap integrates TCM with modern medicine in common aspects at both the phenotypic and molecular levels and inferred all pairwise relationships among SymMap components using statistical tests to give pharmaceutical scientists the ability to rank and filter promising results to guide drug discovery.
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Cytoplasmic Assembly and Selective Nuclear Import of Arabidopsis ARGONAUTE4/siRNA Complexes

TL;DR: This study unexpectedly found that hc-siRNAs are predominantly present in the cytoplasm and proposes that selective nuclear import of mature AGO4/siRNA complexes is a key regulatory point prior to the effector stage of RdDM.
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Gene silencing by artificial microRNAs in Chlamydomonas

TL;DR: An artificial miRNA-based strategy to knock down gene expression in Chlamydomonas is developed and two artificial miRNAs (amiRNAs) targeting the MAA7 and RBCS1/2 genes, respectively are constructed.