Weidong Wu

TL;DR: The present understanding of COVID-19 is detailed and the current state of development of measures are introduced in this review to provide a comprehensive summary to public health authorities and potential readers worldwide.

TL;DR: Elucidation of antiviral and inflammatory cellular signaling pathways initiated by EV71 will not only help uncover the potential mechanisms of EV 71 infection-induced pathogenesis, but will also provide clues for the design of therapeutic strategies against EV71 infection.

TL;DR: Global transcriptome analysis of lncRNA and mRNA expression profiles in EV71-infected human rhabdomyosarcoma cells and skeletal muscle of mice using second-generation sequencing suggests that lncRNAs may participate in EV 71 infection-induced pathogenesis through regulating immune responses, protein binding, cellular component biogenesis and metabolism.

TL;DR: Recognizing how EVs linked to HFMD evade host innate immune system, the interactions between them are described and future directions to better inform drug development and public health are suggested.

TL;DR: Water-soluble fraction of PM2.5 were found responsible for the enhancement of FcεRI-mediated signaling, mast cell degranulation, and cytokine production, and the data suggest that PM 2.5 could affect mast cell activation through enhancing Fc�RI- mediated signaling.