W
Weipan Xu
Researcher at Chinese Academy of Sciences
Publications - 6
Citations - 324
Weipan Xu is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Environmental exposure & Arsenic toxicity. The author has an hindex of 6, co-authored 6 publications receiving 268 citations.
Papers
More filters
Journal ArticleDOI
Urinary metabolic biomarkers link oxidative stress indicators associated with general arsenic exposure to male infertility in a han chinese population.
Heqing Shen,Weipan Xu,Jie Zhang,Minjian Chen,Francis Martin,Yankai Xia,Liangpo Liu,Sijun Dong,Yong-Guan Zhu +8 more
TL;DR: It is shown that elevated urinary concentrations of Asi(V) from general As exposure are significantly associated with male infertility, and As species may exert toxicity via oxidative stress and sexual hormone disrupting mechanisms, as indicated by related biomarkers.
Journal ArticleDOI
Environmental exposure to arsenic may reduce human semen quality: associations derived from a Chinese cross-sectional study
Weipan Xu,Huaqiong Bao,Feng Liu,Liangpo Liu,Yong-Guan Zhu,Jianwen She,Sijun Dong,Min Cai,Lianbing Li,Chuanhai Li,Heqing Shen +10 more
TL;DR: Reduced parameters in human semen quality are positively associated with As exposure in a reproductive-age Chinese cohort after adjusting for age, body mass index, abstinence, smoking and drinking habits.
Journal ArticleDOI
Urinary metabolomics revealed arsenic internal dose-related metabolic alterations: a proof-of-concept study in a Chinese male cohort.
Jie Zhang,Heqing Shen,Weipan Xu,Yankai Xia,Dana B. Barr,Xiaoli Mu,Xiaoxue Wang,Liangpo Liu,Qingyu Huang,Meiping Tian +9 more
TL;DR: This study demonstrated that metabolomics can be used to investigate arsenic-related biomarkers of metabolic changes; the dose-dependent trends of arsenic exposure to these biomarkers may translate into the potential use of metabolic biomarkers in arsenic risk assessment.
Journal ArticleDOI
Low-level environmental arsenic exposure correlates with unexplained male infertility risk.
Xiaofei Wang,Jie Zhang,Weipan Xu,Qingyu Huang,Liangpo Liu,Meiping Tian,Yankai Xia,Weibing Zhang,Heqing Shen +8 more
TL;DR: Findings provide evidences that low-level environmental arsenic exposure was positively associated with UMI risk and through the logistic regression analysis, observed that the urine Asi(V) level and PMI were most significantly associated withUMI risk among the observations.
Journal ArticleDOI
Exposure to arsenic via drinking water induces 5-hydroxymethylcytosine alteration in rat
Jie Zhang,Xiaoli Mu,Weipan Xu,Francis Martin,Ambreen Alamdar,Liangpo Liu,Meiping Tian,Qingyu Huang,Heqing Shen +8 more
TL;DR: It is suggested that 5hmC is a more sensitive biomarker of arsenic-induced impacts on epigenetic processes than 5mC, and demethylation via hydroxymethylcytosine appears to play a central role in the toxic mechanism of arsenic.