scispace - formally typeset
W

Wen Cheng Xiong

Researcher at Case Western Reserve University

Publications -  209
Citations -  13860

Wen Cheng Xiong is an academic researcher from Case Western Reserve University. The author has contributed to research in topics: Neuromuscular junction & Agrin. The author has an hindex of 64, co-authored 194 publications receiving 12171 citations. Previous affiliations of Wen Cheng Xiong include Charlie Norwood VA Medical Center & Georgia Regents University.

Papers
More filters
Book ChapterDOI

General introduction to in situ hybridization protocol using nonradioactively labeled probes to detect mRNAs on tissue sections

Daehoon Lee, +2 more
- 01 Jan 2013 - 
TL;DR: The efficient ISH protocol for nonradioactive (i.e., in direct methods using digoxigenin (DIG) system) RNA probes, and it can be performed in less than 3 days is described.
Journal ArticleDOI

pHluorin-BACE1-mCherry Acts as a Reporter for the Intracellular Distribution of Active BACE1 In Vitro and In Vivo

Lu Zhao, +10 more
- 17 May 2019 - 
TL;DR: P pHluorin-BACE1-mCherry fusion protein may serve as a useful tool for visualizing active/inactive BACE1 in culture and in vivo, and (pro)renin receptor (PRR), a subunit of the v-ATPase complex, regulates pHLUorin’s fluorescence and Bace1 activity in pHluorbase expressing cells.
Journal ArticleDOI

PRRT2 frameshift mutation reduces its mRNA stability resulting loss of function in paroxysmal kinesigenic dyskinesia

Yongcheng Pan, +11 more
- 12 Feb 2020 - 
TL;DR: These studies suggest that PRRT2 frameshift mutation leads to the loss of function by affecting its mRNA stability, a mechanism that is different from haploinsufficiency due to dysfunctional protein or gain of function caused by truncated protein.
Journal ArticleDOI

Human antigen R-regulated mRNA metabolism promotes the cell motility of migrating mouse neurons

Yi-Fei Zhao, +9 more
- 01 Jan 2020 - 
TL;DR: It is reported that HuR is expressed in postmitotic projection neurons during mouse brain development and data reveal a post-transcriptional mechanism that maintains actin dynamics during neuronal migration, crucial for cell motility.
Posted ContentDOI

Myosin X interaction with KIF13B, a crucial pathway for Netrin-1-induced axonal development

Hua-Li Yu, +24 more
- 06 Jan 2020 - 
TL;DR: Evidence is provided for Myo X-KIF13B as a critical pathway for Netrin-1 promoted axon initiation and branching/targeting in mouse neocortex and it is suggested that this pathway is also important for cell adhesion, migration, and neuronal axon guidance in vivo.