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Wendy K. Chung
Researcher at Columbia University
Publications - 40
Citations - 2601
Wendy K. Chung is an academic researcher from Columbia University. The author has contributed to research in topics: Population & Genome-wide association study. The author has an hindex of 13, co-authored 40 publications receiving 1567 citations. Previous affiliations of Wendy K. Chung include Columbia University Medical Center & New York University.
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Psychotic symptoms in 16p11.2 copy number variant carriers
Amandeep Jutla,Amandeep Jutla,J. Blake Turner,J. Blake Turner,LeeAnne Green Snyder,Wendy K. Chung,Jeremy Veenstra-VanderWeele,Jeremy Veenstra-VanderWeele,Jeremy Veenstra-VanderWeele +8 more
TL;DR: It is found that having the duplication or having an autism diagnosis may increase the risk of psychosis, a key feature of schizophrenia, in a sample of 16p11.2 deletion and duplication carriers.
Journal ArticleDOI
Identification of a secondary RET mutation in a pediatric patient with relapsed acute myeloid leukemia leads to the diagnosis and treatment of asymptomatic metastatic medullary thyroid cancer in a parent: a case for sequencing the germline.
Danielle Pendrick,Jennifer A. Oberg,Susan J. Hsiao,Wendy K. Chung,Carrie Koval,Anthony N. Sireci,Jennifer H. Kuo,Prakash Satwani,Chana L. Glasser,Maria Luisa Sulis,Mahesh Mansukhani,Julia L. Glade Bender,Julia L. Glade Bender +12 more
TL;DR: A case in which a RET variant was identified in a 3-yr-old male with relapsed leukemia, revealing the patient's father and three siblings carried the same variant, associated with multiple endocrine neoplasia 2A (MEN2A).
Journal ArticleDOI
Robust identification of deletions in exome and genome sequence data based on clustering of Mendelian errors.
Kathryn B. Manheimer,Nihir Patel,Felix Richter,Joshua M. Gorham,Angela C. Tai,Jason Homsy,Marko T. Boskovski,Michael Parfenov,Elizabeth Goldmuntz,Elizabeth Goldmuntz,Wendy K. Chung,Martina Brueckner,Martin Tristani-Firouzi,Deepak Srivastava,Deepak Srivastava,Jonathan G. Seidman,Christine E. Seidman,Christine E. Seidman,Christine E. Seidman,Bruce D. Gelb,Andrew J. Sharp +20 more
TL;DR: Using the Mendelian Error Method (MEM), 127 deletions were identified in 2,601 WES trios from the Pediatric Cardiac Genomics Consortium, with a validation rate of 88% by digital droplet PCR and an orthogonal approach for verifying deletions called by other tools.
Posted ContentDOI
Deep whole genome sequencing of multiple proband tissues and parental blood reveals the complex genetic etiology of congenital diaphragmatic hernias
Eric L. Bogenschutz,Zachary D. Fox,Andrew Farrell,Julia Wynn,Barry Moore,Lan Yu,Gudrun Aspelund,Gabor T. Marth,Mark Yandell,Yufeng Shen,Wendy K. Chung,Wendy K. Chung,Gabrielle Kardon +12 more
TL;DR: A comprehensive reconstruction of the genetic architecture of four patients with isolated CDH individuals demonstrates that the etiology of congenital diaphragmatic hernia is heterogeneous and multifactorial.
Journal ArticleDOI
Abnormal Auditory Mismatch Fields in Children and Adolescents With 16p11.2 Deletion and 16p11.2 Duplication.
Junko Matsuzaki,Jeffrey I. Berman,Lisa Blaskey,Emily S. Kuschner,Leah Gaetz,Pratik Mukherjee,Randy L. Buckner,Srikantan S. Nagarajan,Wendy K. Chung,Elliott H. Sherr,Timothy P.L. Roberts,Timothy P.L. Roberts +11 more
TL;DR: These findings suggest that auditory MMF response delays are associated with clinical severity of language and cognitive impairment in individuals with either 16p 11.2 deletion or 16p11.2 duplication.