Wenhao Zhou

TL;DR: The results suggest that abnormalities of centrosomal function and chromatin remodeling of the microcephaly-associated genes may be implicated in pathogenesis of ASD.

TL;DR: PhenoPro can be used as a pre-screening tool to assist in the diagnosis of Mendelian disease genes and is benchmarked using both simulated patients and real diagnosed patients of Chinese ancestry, and shows significant improvements.

TL;DR: The results suggested that the mutations of SETD1A play a fundamental role in abnormal synaptic function and the development of neurons, so they may be pathogenic factors for neurodevelopmental disorders.

TL;DR: It is suggested that hypothermia has the effects to protect OPC and to promote OL maturation and myelin repair in hypoxic-ischemic events in the neonatal rat brain.

TL;DR: This review focuses on the essential role of the PTEN signaling pathway in neuronal differentiation and the formation of neural circuitry, as well as genetic mouse models with Pten manipulations that suggest that the effect of PTEN on neural stem-cell development contributes significantly to the pathophysiology of autism spectrum disorders.