W
Wenhui Gao
Researcher at Canadian Institutes of Health Research
Publications - 2
Citations - 201
Wenhui Gao is an academic researcher from Canadian Institutes of Health Research. The author has contributed to research in topics: Lipolysis & Adipocyte. The author has an hindex of 2, co-authored 2 publications receiving 195 citations.
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Journal ArticleDOI
Carboxylesterase 3 (EC 3.1.1.1) is a major adipocyte lipase.
Krishnakant G. Soni,Richard Lehner,Pavel Metalnikov,Paul O'Donnell,Meriem Semache,Wenhui Gao,Keith Ashman,Alexey V. Pshezhetsky,Grant A. Mitchell +8 more
TL;DR: Functional proteomics was used to detect non-HSL lipase(s) in mouse WAT and discovered two peaks of esterase activity using p-nitrophenyl butyrate as a substrate, which contained most of the lipase activity.
Journal ArticleDOI
Attenuation of adipocyte triacylglycerol hydrolase activity decreases basal fatty acid efflux.
TL;DR: Inhibition of TGH-mediated lipolysis did not affect insulin-stimulated Glut4 translocation from intracellular compartments to the plasma membrane or glucose uptake into adipocytes, suggesting that TGH plays a role in adipose tissue triacylglycerol metabolism and may be a suitable pharmacological target for lowering fatty acid efflux from adipose tissues without altering glucose import.