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William A. Blattner

Researcher at University of Maryland, Baltimore

Publications -  345
Citations -  26953

William A. Blattner is an academic researcher from University of Maryland, Baltimore. The author has contributed to research in topics: Population & Virus. The author has an hindex of 80, co-authored 345 publications receiving 26023 citations. Previous affiliations of William A. Blattner include RTI International & Boston University.

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Journal ArticleDOI

Cryopreservation and long‐term liquid nitrogen storage of peripheral blood mononuclear cells for flow cytometry analysis effects on cell subset proportions and fluorescence intensity

TL;DR: Cryopreservation is a valuable technique for longterm storage of viable cells and for clinical and epidemiological investigations encompassing large numbers of samples, statistical techniques to adjust for small changes during storage should be considered.
Journal Article

HTLV-I serostatus of mothers of patients with adult T-cell leukemia and HTLV-I-associated myelopathy/tropical spastic paraparesis.

TL;DR: This study confirms that infection with HTLV-I in early childhood can lead to ATL in later life, and that HAM/TSP can also result from early infection but more commonly results from infection acquired in adulthood.
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C-terminal fragments of gp120 and synthetic peptides from five HTLV-III strains: prevalence of antibodies to the HTLV-III-MN isolate in infected individuals.

TL;DR: Patients' sera cross reactivity to multiple strains of the principal neutralizing domain may reflect the antigenic relatedness of the virus isolates rather than multiple infection events or strains generated during disease progression.
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Trends in antiretroviral therapy and mother-infant transmission of HIV. The Women and Infants Transmission Study Group.

TL;DR: In this paper, trends in the vertical transmission rate of HIV and evolving antiretroviral usage between 1990 and 1998 within the Women and Infants Transmission Study were evaluated, and a decline in mother-infant transmission was temporally associated with advances in therapy, especially when regimens including a protease inhibitor.
Journal Article

Detection of both mutant and wild-type p53 protein in normal skin fibroblasts and demonstration of a shared 'second hit' on p53 in diverse tumors from a cancer-prone family with Li-Fraumeni syndrome.

TL;DR: It is demonstrated that normal skin fibroblasts derived from members of a family with Li-Fraumeni syndrome express mutant p53Gly----Asp(245) protein and RNA at levels similar to the wild-type p53, which further support the notion that germline p53 mutation plays a key role in the tumorigenesis of individuals withLi-Fraumei syndrome.