Jeffrey G. Edwards

TL;DR: It is reported that AMPA receptors are transported from recycling endosomes to the plasma membrane for LTP and provide a mechanistic link between synaptic potentiation and membrane remodeling during synapse modification.

TL;DR: It is demonstrated that myosin Vb (MyoVb), a Ca2+-sensitive motor, conducts spine trafficking during long-term potentiation (LTP) of synaptic strength, providing a mechanistic link between the induction and expression of postsynaptic plasticity.

TL;DR: The results suggest that, in the hippocampus, TRPV1 receptor activation selectively modifies synapses onto interneurons, which may have a role in long-term changes in physiological and pathological circuit behavior during learning and epileptic activity.

TL;DR: Nasopharyngeal and oral carcinoma patients from Malaysia, Hong Kong and Sri Lanka who have very high EBV titres show that there is little, if any, cross-reactivity between antibodies to these two gamma viruses, suggesting that human herpes virus-8 (HHV-8) may be either a recently introduced virus or one that has extremely low infectivity.

TL;DR: Rates of disseminated MAC in AIDS are higher in developed than developing countries and are due to both differences in exposure and differences in immunity, providing a rationale for prevention of MAC through both active immunization and reduction in exposure to the organism.