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William G. Austen
Researcher at Harvard University
Publications - 382
Citations - 15570
William G. Austen is an academic researcher from Harvard University. The author has contributed to research in topics: Mastectomy & Breast reconstruction. The author has an hindex of 60, co-authored 363 publications receiving 14548 citations. Previous affiliations of William G. Austen include Beth Israel Deaconess Medical Center & NewYork–Presbyterian Hospital.
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Journal ArticleDOI
Murine hindlimb reperfusion injury can be initiated by a self-reactive monoclonal IgM.
William G. Austen,Ming Zhang,Rodney K. Chan,Daniel S. Friend,Herbert B. Hechtman,Michael C. Carroll,Francis D. Moore +6 more
TL;DR: A single clone of self-reactive IgM, CM22, can initiate complement-dependent I/R injury, and this injury was 137% greater than in both Cr2-/- mice reconstituted with saline and those reconstitute with a different IgM clone, CM31.
Journal Article
Quantitative correlation of distal arterial outflow and patency of femoropopliteal reversed saphenous vein grafts with intraoperative flow and pressure measurements.
Eldred D. Mundth,Darling Rc,John M. Moran,Mortimer J. Buckley,Robert R. Linton,William G. Austen +5 more
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The differing roles of the classical and mannose-binding lectin complement pathways in the events following skeletal muscle ischemia-reperfusion.
Rodney K. Chan,Shahrul I. Ibrahim,Kazue Takahashi,Edwin Kwon,Michael C. McCormack,Alan Ezekowitz,Michael C. Carroll,Francis D. Moore,William G. Austen +8 more
TL;DR: Data indicate that blockade of the classical pathway alone (C1q) is protective against permeability edema and remote pulmonary injury but not protective against histologic muscle injury, and that blocking the MBL pathway alone protects against histological injury but is not Protective against permeable edema or lung injury.
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The Use of CO2 Fractional Photothermolysis for the Treatment of Burn Scars.
Benjamin Levi,Amir Ibrahim,Katie Mathews,Brandon M. Wojcik,Jason Gomez,Shawn P. Fagan,William G. Austen,Jeremy Goverman +7 more
TL;DR: Fractional photothermolysis utilizing the CO2 laser is a safe and effective modality for the treatment of symptomatic burn scars, donor sites, and skin grafts, and patient satisfaction with this procedure is high, and complications are low.
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Ultrapure, stroma-free, polymerized bovine hemoglobin solution: evaluation of renal toxicity.
TL;DR: This study shows that UPPBHg may be administered in very large doses with only mild, reversible renal toxicity, and observation that urine alkalinization ameliorates this toxicity suggests that this may occur by hemoglobin precipitation or by a toxic effect in the renal tubules.