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Wolfgang Hamel
Researcher at University of Hamburg
Publications - 94
Citations - 6203
Wolfgang Hamel is an academic researcher from University of Hamburg. The author has contributed to research in topics: Deep brain stimulation & Subthalamic nucleus. The author has an hindex of 31, co-authored 81 publications receiving 5443 citations. Previous affiliations of Wolfgang Hamel include University of Kiel.
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Journal ArticleDOI
A Randomized Trial of Deep-Brain Stimulation for Parkinson's Disease
Günther Deuschl,Carmen Schade-Brittinger,Paul Krack,Jens Volkmann,Helmut Schäfer,Kai Bötzel,C. Daniels,Angela Deutschländer,Ulrich Dillmann,Wilhelm Eisner,Doreen Gruber,Wolfgang Hamel,Jan Herzog,Rüdiger Hilker,Stephan Klebe,Manja Kloss,J. Koy,Martin Krause,Andreas Kupsch,Delia Lorenz,Stefan Lorenzl,H. Maximilian Mehdorn,Jean Richard Moringlane,Wolfgang H. Oertel,Marcus O. Pinsker,Heinz Reichmann,Alexander Reuss,Gerd-Helge Schneider,Alfons Schnitzler,Ulrich Steude,Volker Sturm,Lars Timmermann,Volker M. Tronnier,Thomas Trottenberg,Lars Wojtecki,Elisabeth Wolf,Werner Poewe,Jürgen Voges +37 more
TL;DR: In this six-month study of patients under 75 years of age with severe motor complications of Parkinson's disease, neurostimulation of the subthalamic nucleus was more effective than medical management alone.
Journal ArticleDOI
Two‐year follow‐up of subthalamic deep brain stimulation in Parkinson's disease
Jan Herzog,Jens Volkmann,Paul Krack,F. Kopper,M. Pötter,Delia Lorenz,Meike Steinbach,Stefan Klebe,Wolfgang Hamel,B. Schrader,D. Weinert,Dieter Müller,Hubertus Maximilian Mehdorn,Günther Deuschl +13 more
TL;DR: The current series demonstrates efficacy and safety of STN‐DBS beyond the first year after surgical procedure, and includes a wide range of psychiatric adverse events which, however, were temporary.
Journal ArticleDOI
Most effective stimulation site in subthalamic deep brain stimulation for Parkinson's disease.
Jan Herzog,Urban M. Fietzek,Wolfgang Hamel,Andre Morsnowski,Frank Steigerwald,B. Schrader,D. Weinert,Gerd Pfister,Dieter Müller,Hubertus Maximilian Mehdorn,Günther Deuschl,Jens Volkmann +11 more
TL;DR: The optimal stimulation site in subthalamic deep brain stimulation was evaluated by correlation of the stereotactic position of the stimulation electrode with the electrophysiologically specified dorsal STN border, and best clinical results with least energy consumption were found in contacts located in the dorsolateral border zone.
Journal ArticleDOI
Deep brain stimulation of the subthalamic nucleus in Parkinson's disease: evaluation of active electrode contacts.
Wolfgang Hamel,Urban M. Fietzek,Andre Morsnowski,B. Schrader,Jan Herzog,D. Weinert,Gerd Pfister,Dieter Müller,Jens Volkmann,Günther Deuschl,Hubertus Maximilian Mehdorn +10 more
TL;DR: Stimulation of the subthalamic nucleus resulted in marked improvement in levodopa sensitive parkinsonian symptoms andlevodopa induced dyskinesias, with significant improvement in UPDRS III scores.
Journal ArticleDOI
Deep brain stimulation of the subthalamic nucleus improves cognitive flexibility but impairs response inhibition in Parkinson disease.
TL;DR: Short-term STN stimulation improves cognitive flexibility (giving up habitual responses) but impairs response inhibition, and long-termSTN stimulation does not change global cognitive function.