A
Andreas Kupsch
Researcher at Otto-von-Guericke University Magdeburg
Publications - 245
Citations - 20974
Andreas Kupsch is an academic researcher from Otto-von-Guericke University Magdeburg. The author has contributed to research in topics: Deep brain stimulation & Subthalamic nucleus. The author has an hindex of 69, co-authored 238 publications receiving 18846 citations. Previous affiliations of Andreas Kupsch include Humboldt University of Berlin & Charité.
Papers
More filters
Journal ArticleDOI
A Randomized Trial of Deep-Brain Stimulation for Parkinson's Disease
Günther Deuschl,Carmen Schade-Brittinger,Paul Krack,Jens Volkmann,Helmut Schäfer,Kai Bötzel,C. Daniels,Angela Deutschländer,Ulrich Dillmann,Wilhelm Eisner,Doreen Gruber,Wolfgang Hamel,Jan Herzog,Rüdiger Hilker,Stephan Klebe,Manja Kloss,J. Koy,Martin Krause,Andreas Kupsch,Delia Lorenz,Stefan Lorenzl,H. Maximilian Mehdorn,Jean Richard Moringlane,Wolfgang H. Oertel,Marcus O. Pinsker,Heinz Reichmann,Alexander Reuss,Gerd-Helge Schneider,Alfons Schnitzler,Ulrich Steude,Volker Sturm,Lars Timmermann,Volker M. Tronnier,Thomas Trottenberg,Lars Wojtecki,Elisabeth Wolf,Werner Poewe,Jürgen Voges +37 more
TL;DR: In this six-month study of patients under 75 years of age with severe motor complications of Parkinson's disease, neurostimulation of the subthalamic nucleus was more effective than medical management alone.
Journal ArticleDOI
Neurostimulation for Parkinson's Disease with Early Motor Complications
W. M. M. Schuepbach,Jörn Rau,Karina Knudsen,Jens Volkmann,Paul Krack,Lars Timmermann,Thomas D. Hälbig,Helke Hesekamp,S. M. Navarro,Niklaus Meier,Daniela Falk,Maximilian Mehdorn,S. Paschen,Mohammad Maarouf,Michael T. Barbe,Gereon R. Fink,Andreas Kupsch,Doreen Gruber,G.-H. Schneider,Eric Seigneuret,Andrea Kistner,Patrick Chaynes,Fabienne Ory-Magne,C. Brefel Courbon,Jan Vesper,Alfons Schnitzler,Lars Wojtecki,Jean-Luc Houeto,Benoit Bataille,David Maltête,P. Damier,Sylvie Raoul,F. Sixel-Doering,D. Hellwig,Alireza Gharabaghi,Rejko Krüger,M. O. Pinsker,Florian Amtage,J. Regis,Tatiana Witjas,Stéphane Thobois,Patrick Mertens,Manja Kloss,Andreas Hartmann,Wolfgang H. Oertel,Bart Post,Hans Speelman,Yves Agid,Carmen Schade-Brittinger,Günther Deuschl +49 more
TL;DR: Subthalamic stimulation was superior to medical therapy in patients with Parkinson's disease and early motor complications and time with good mobility and no dyskinesia.
Journal ArticleDOI
Pallidal Deep-Brain Stimulation in Primary Generalized or Segmental Dystonia
Andreas Kupsch,Reiner Benecke,Jörg Müller,Thomas Trottenberg,Gerd-Helge Schneider,Werner Poewe,Wilhelm Eisner,Alexander Wolters,Jan-Uwe Müller,Günther Deuschl,Marcus O. Pinsker,Inger Marie Skogseid,Geir Ketil Roeste,Juliane Vollmer-Haase,Angela Brentrup,Martin Krause,Volker M. Tronnier,Alfons Schnitzler,Jürgen Voges,Guido Nikkhah,Jan Vesper,Markus Naumann,Jens Volkmann +22 more
TL;DR: Bilateral pallidal neurostimulation for 3 months was more effective than sham stimulation in patients with primary generalized or segmental dystonia and sustained improvement in all movement symptoms, the level of disability, and quality of life, as compared with baseline scores.
Journal ArticleDOI
Reduction in subthalamic 8-35 Hz oscillatory activity correlates with clinical improvement in Parkinson's disease.
TL;DR: A link between levodopa‐induced improvements in bradykinesia and rigidity and reductions in population synchrony at frequencies < 35 Hz in the region of the STN in patients with PD is supported.
Journal ArticleDOI
High-frequency stimulation of the subthalamic nucleus suppresses oscillatory beta activity in patients with Parkinson's disease in parallel with improvement in motor performance.
Andrea A. Kühn,Florian Kempf,Christof Brücke,Louise Gaynor Doyle,Irene Martinez-Torres,Alek Pogosyan,Thomas Trottenberg,Andreas Kupsch,Gerd-Helge Schneider,Marwan Hariz,Wim Vandenberghe,Bart Nuttin,Peter Brown +12 more
TL;DR: The findings suggest that HFS may act by modulating pathological patterns of synchronized oscillations, specifically by reduction of pathological β activity in PD.