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Won Ki Kang
Researcher at Samsung Medical Center
Publications - 385
Citations - 18420
Won Ki Kang is an academic researcher from Samsung Medical Center. The author has contributed to research in topics: Cancer & Capecitabine. The author has an hindex of 59, co-authored 368 publications receiving 14746 citations. Previous affiliations of Won Ki Kang include Sungkyunkwan University & Samsung.
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Journal ArticleDOI
Nivolumab in patients with advanced gastric or gastro-oesophageal junction cancer refractory to, or intolerant of, at least two previous chemotherapy regimens (ONO-4538-12, ATTRACTION-2): a randomised, double-blind, placebo-controlled, phase 3 trial
Yoon-Koo Kang,Narikazu Boku,Taroh Satoh,Min Hee Ryu,Yee Chao,Ken Kato,Hyun Cheol Chung,Jen-Shi Chen,Kei Muro,Won Ki Kang,Kun-Huei Yeh,Takaki Yoshikawa,Sang Cheul Oh,Li Yuan Bai,Takao Tamura,Keun Wook Lee,Yasuo Hamamoto,Jong Gwang Kim,Keisho Chin,Do Youn Oh,Keiko Minashi,Jae Yong Cho,Masahiro Tsuda,Li-Tzong Chen,Li-Tzong Chen +24 more
TL;DR: In this phase 3 study, the survival benefits indicate that nivolumab might be a new treatment option for heavily pretreated patients with advanced gastric or gastro-oesophageal junction cancer.
Journal ArticleDOI
Molecular analysis of gastric cancer identifies subtypes associated with distinct clinical outcomes
Razvan Cristescu,Jeeyun Lee,Michael Nebozhyn,Kyoung-Mee Kim,Jason C. Ting,Swee Seong Wong,Jiangang Liu,Yong Gang Yue,Jian Wang,Kun Yu,Xiang S. Ye,In-Gu Do,Shawn Liu,Lara Gong,Jake Fu,Jason Gang Jin,Min Gew Choi,Tae Sung Sohn,Joon-Ho Lee,Jae Moon Bae,Seung Tae Kim,Se Hoon Park,Insuk Sohn,Sin-Ho Jung,Patrick Tan,Ronghua Chen,James S. Hardwick,Won Ki Kang,Mark Ayers,Dai Hongyue,Christoph Reinhard,Andrey Loboda,Sung Kim,Amit Aggarwal +33 more
TL;DR: This work uses gene expression data to describe four molecular subtypes linked to distinct patterns of molecular alterations, disease progression and prognosis in gastric cancer, and describes key molecular alterations in each of the four subtypes using targeted sequencing and genome-wide copy number microarrays.
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Comprehensive molecular characterization of clinical responses to PD-1 inhibition in metastatic gastric cancer
Seung Tae Kim,Razvan Cristescu,Adam J. Bass,Kyoung-Mee Kim,Justin I. Odegaard,Kyung Kim,Xiaoqiao Liu,Xinwei Sher,Hun Jung,Mijin Lee,Su Jin Lee,Se Hoon Park,Joon Oh Park,Young Suk Park,Ho Yeong Lim,Hyuk Lee,Min-Gew Choi,Amir Ali Talasaz,Peter Soonmo Kang,Jonathan D. Cheng,Andrey Loboda,Jeeyun Lee,Won Ki Kang +22 more
TL;DR: Findings provide insight into the molecular features associated with response to pembrolizumab in patients with mGC and provide biomarkers potentially relevant for the selection of patients who may derive greater benefit from PD-1 inhibition.
Journal ArticleDOI
Phase III Trial Comparing Capecitabine Plus Cisplatin Versus Capecitabine Plus Cisplatin With Concurrent Capecitabine Radiotherapy in Completely Resected Gastric Cancer With D2 Lymph Node Dissection: The ARTIST Trial
Jeeyun Lee,Do Hoon Lim,Sung Kim,Se Hoon Park,Joon Oh Park,Young Suk Park,Ho Yeong Lim,Min Gew Choi,Tae Sung Sohn,Jae Hyung Noh,Jae Moon Bae,Yong Chan Ahn,Insuk Sohn,Sin-Ho Jung,Sin-Ho Jung,Cheol Keun Park,Kyoung-Mee Kim,Won Ki Kang +17 more
TL;DR: The addition of XRT to XP chemotherapy did not significantly reduce recurrence after curative resection and D2 lymph node dissection in Gastric cancer and a subsequent trial (ARTIST-II) in patients with lymph node-positive gastric cancer is planned.
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Salvage Chemotherapy for Pretreated Gastric Cancer: A Randomized Phase III Trial Comparing Chemotherapy Plus Best Supportive Care With Best Supportive Care Alone
Jung Hun Kang,Soon Il Lee,Do Hyoung Lim,Keon Woo Park,Sung Yong Oh,Hyuk Chan Kwon,In Gyu Hwang,Sang Cheol Lee,Eun Mi Nam,Dong Bok Shin,Jeeyun Lee,Joon Oh Park,Young Suk Park,Ho Yeong Lim,Won Ki Kang,Se Hoon Park +15 more
TL;DR: To the authors' knowledge, this is the largest phase III trial comparing SLC plus BSC with BSC alone in AGC and in pretreated patients, SLC is tolerated and significantly improves OS when added to BSC.