Jiangang Liu

TL;DR: This work uses gene expression data to describe four molecular subtypes linked to distinct patterns of molecular alterations, disease progression and prognosis in gastric cancer, and describes key molecular alterations in each of the four subtypes using targeted sequencing and genome-wide copy number microarrays.

TL;DR: Findings from a whole-genome sequencing study of 88 matched HCC tumor/normal pairs, 81 of which are Hepatitis B virus (HBV) positive, find beta-catenin to be the mostrequently mutated oncogene and TP53 the most frequently mutated tumor suppressor.

TL;DR: It is suggested that a genomics-based systems approach focused on the tumor stroma can be used to discover putative predictive biomarkers of treatment response, especially to antiangiogenesis agents and immunotherapy, thus offering an opportunity to improve patient stratification.

TL;DR: Mechanistic studies reveal that USF1 promotes GSC's stemness by directly regulating CD90 expression, and the overexpression of CD90 restores the stemness property in USf1 knockdown GSCs and its immunosuppressive microenvironment.

TL;DR: Plasma Gal-3 might be employed as an additional predictor for new-onset HFpEF, the adverse prognosis inHFpEF patients (all-cause death, the composite endpoints of all- cause death and HF hospitalization or CV death andHF hospitalization), and the severity of LVDD in HFp EF populations.