Xiangxin Lou

TL;DR: Biological assay results corroborated that the fibrous PLMC scaffolds were cytocompatible by supporting osteoblast adhesion and proliferation, and functionally promoted biomineralization-relevant alkaline phosphatase expression and mineral deposition.

TL;DR: Investigation of osteogenic differentiation and bone regeneration capacities of iPSC-MSCs by using biomimetic nanofibers of hydroxyapatite/collagen/chitosan (HAp/Col/CTS) suggests that nan ofibrous scaffold supported iPSSCs complex may be a new 'stem cell-scaffold' system for regulating the fate of osteogenicity towards patient-specific bone regeneration in future.

TL;DR: This study suggests that introduction of an elliptical nano-pore feature to the aligned microfiber surfaces could provide additional dimensionality of topographical cues to modulate the vSMC responses when using the aligned electrospun ultrafine fibers for engineering vascular constructs.

TL;DR: The results suggest that crosslinking with the 0.5% GP in PBS could yield CTS nanofibers with improved wet stability in nanofiber structure and optimized mechanical and biological performances.

TL;DR: High-intensity focused ultrasound (HIFU) was employed as a unique technique to enable shape memory and payload release effects of the three-dimensional (3-D) structure to be demonstrated, finding that incorporation of CTS into PLGA microspheres could regulate the transition temperature Ttrans of the microsphere and affect shape memory ratio of the fabricated cylindrical rod to some extent.