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Xiao-Hong Nancy Xu

Researcher at Old Dominion University

Publications -  53
Citations -  3484

Xiao-Hong Nancy Xu is an academic researcher from Old Dominion University. The author has contributed to research in topics: Nanoparticle & Efflux. The author has an hindex of 28, co-authored 52 publications receiving 3221 citations. Previous affiliations of Xiao-Hong Nancy Xu include French Alternative Energies and Atomic Energy Commission & United States Department of Energy.

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In vivo imaging of transport and biocompatibility of single silver nanoparticles in early development of zebrafish embryos.

TL;DR: The transport of single silver nanoparticles into an in vivo model system (zebrafish embryos) and investigated their effects on early embryonic development at single-nanoparticle resolution in real time found that single Ag nanoparticles are transported into and out of embryos through chorion pore canals and exhibit Brownian diffusion (not active transport).
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Real-Time Probing of Membrane Transport in Living Microbial Cells Using Single Nanoparticle Optics and Living Cell Imaging†

TL;DR: Assessment of real-time change of membrane permeability and pore sizes of P. aeruginosa using the intrinsic color index (surface plasmon resonance spectra) of silver (Ag) nanoparticles as the nanometer size index probes shows that Ag nanoparticles with sizes ranging up to 80 nm are accumulated in living microbial cells, demonstrating that these Ag nanoparticle transport through the inner and outer membrane of the cells.
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Synthesis and characterization of tunable rainbow colored colloidal silver nanoparticles using single-nanoparticle plasmonic microscopy and spectroscopy

TL;DR: This study synthesized twelve colloids of Ag NPs and correlated the sizes and shapes of single NPs determined by high-resolution transmission electron microscopy with scattering localized surface plasmon resonance (LSPR) spectra ofsingle NPs characterized by dark-field optical microcopy and spectroscopy (DFOMS).
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Long-range electrostatic trapping of single-protein molecules at a liquid-solid interface.

TL;DR: The motion of single, dye-labeled protein molecules was monitored at various pH and ionic strengths within the 180-nanometer-thick evanescent-field layer at a fused-silica surface, implying that surface charge can influence the charged protein at distances beyond that of the electrical double-layer thickness.
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Random walk of single gold nanoparticles in zebrafish embryos leading to stochastic toxic effects on embryonic developments

TL;DR: The results show that Au nanoparticles are much more biocompatible with (less toxic to) the embryos than the Ag nanoparticles that were reported previously, suggesting that they are better suited as biocombatible probes for imaging embryos in vivo.