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Xiao-Ling Tang
Researcher at Zhejiang University of Technology
Publications - 49
Citations - 576
Xiao-Ling Tang is an academic researcher from Zhejiang University of Technology. The author has contributed to research in topics: Chemistry & Tyrosine phenol-lyase. The author has an hindex of 10, co-authored 40 publications receiving 427 citations. Previous affiliations of Xiao-Ling Tang include Zhejiang University.
Papers
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Journal ArticleDOI
Recent advances in biotechnological applications of alcohol dehydrogenases
Yu-Guo Zheng,Huan-Huan Yin,Dao-Fu Yu,Xiang Chen,Xiao-Ling Tang,Zhang Xiaojian,Ya-Ping Xue,Ya-Jun Wang,Zhiqiang Liu +8 more
TL;DR: An overview of biotechnological applications for ADHs in the production of chiral pharmaceuticals and fine chemicals is provided.
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Enzymatic synthesis of an ezetimibe intermediate using carbonyl reductase coupled with glucose dehydrogenase in an aqueous-organic solvent system
Zhiqiang Liu,Si-Chuan Dong,Huan-Huan Yin,Ya-Ping Xue,Xiao-Ling Tang,Zhang Xiaojian,Jun-Yao He,Yu-Guo Zheng +7 more
TL;DR: Recombinant Escherichia coli expressing carbonyl reductase (CBR) was successfully constructed in this study and the highest values reported to date for the production of (S)-ET-5 were reported.
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Metabolic engineering of Escherichia coli for microbial production of L-methionine.
Jian-Feng Huang,Zhiqiang Liu,Li-Qun Jin,Xiao-Ling Tang,Zhen-Yang Shen,Huan-Huan Yin,Yu-Guo Zheng +6 more
TL;DR: This novel metabolically tailored strain of E. coli provided an efficient platform for microbial production of L‐methionine and was engineered via deletion of a negative transcriptional regulator and over‐expression of homoserine O‐succinyltransferase MetA together with efflux transporter YjeH to overproduction.
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Biochemical characterization of a novel tyrosine phenol-lyase from Fusobacterium nucleatum for highly efficient biosynthesis of l-DOPA.
TL;DR: A novel TPL from Fusobacterium nucleatum was successfully overexpressed in Escherichia coli and screened for l-DOPA synthesis with a specific activity of 2.69Umg-1 and the results demonstrated the great potential of Fn-TPL for industrial production of l-dihydroxyphenylalanine.
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Enhanced activity of Thermomyces lanuginosus lipase by site-saturation mutagenesis for efficient biosynthesis of chiral intermediate of pregabalin
TL;DR: Encouraging results demonstrated the great potential of the modified TLL for efficient production of ( S )-2-carboxyethyl-3-cyano-5-methylhexaoic acid used as chiral intermediate for pregabalin.