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Xiao Ou Mao
Researcher at Buck Institute for Research on Aging
Publications - 70
Citations - 13692
Xiao Ou Mao is an academic researcher from Buck Institute for Research on Aging. The author has contributed to research in topics: Neurogenesis & Subventricular zone. The author has an hindex of 50, co-authored 70 publications receiving 13133 citations.
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Journal ArticleDOI
Cyclic AMP response element binding protein (CREB) and CREB binding protein (CBP) in global cerebral ischemia.
TL;DR: Results support a role for transcriptional activation by CREB and CBP in neuronal cell-survival programs following cerebral ischemia.
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Effect of aging on neuroglobin expression in rodent brain.
Yunjuan Sun,Kunlin Jin,Xiao Ou Mao,Lin Xie,Alyson Peel,Jocelyn Childs,Anna Logvinova,Xiaojuan Wang,David A. Greenberg +8 more
TL;DR: The authors found widespread expression of Neuroglobin (Ngb) protein in neurons, but not astrocytes, of several brain regions that are prominently involved in age-related neurodegenerative disorders.
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Heparin-binding epidermal growth factor-like growth factor stimulates cell proliferation in cerebral cortical cultures through phosphatidylinositol 3'-kinase and mitogen-activated protein kinase.
TL;DR: Findings help to clarify the molecular mechanisms through which HB‐EGF operates and enhance phosphorylation of Akt and ERK, implying a role for PI3K/Akt and MEK/ERK signaling in HB‐ EGF‐stimulated cell proliferation.
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Expression level of vascular endothelial growth factor in hippocampus is associated with cognitive impairment in patients with Alzheimer's disease.
TL;DR: The data suggest that VEGF level is associated with progressive loss of cognitive function in patients with AD.
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Pharmacological Induction of Neuroglobin Expression
TL;DR: Ngb expression was increased by the short-chain fatty acids cinnamic acid and valproic acid, but not by other short- chain fatty acids, histone deacetylase inhibitors, or anticonvulsants, which may have therapeutic potential in the treatment of stroke and other neurological disorders.