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Xiao Ou Mao
Researcher at Buck Institute for Research on Aging
Publications - 70
Citations - 13692
Xiao Ou Mao is an academic researcher from Buck Institute for Research on Aging. The author has contributed to research in topics: Neurogenesis & Subventricular zone. The author has an hindex of 50, co-authored 70 publications receiving 13133 citations.
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Journal ArticleDOI
Bax κ, a novel Bax splice variant from ischemic rat brain lacking an ART domain, promotes neuronal cell death
Kunlin Jin,Steven H. Graham,Xiao Ou Mao,Xiangjun He,Tetsuya Nagayama,Roger P. Simon,David A. Greenberg +6 more
TL;DR: The results suggest that the Bax κ may have a role in ischemic neuronal death.
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Electrophysiological neurodifferentiation of subventricular zone-derived precursor cells following stroke
TL;DR: Patch-clamp studies on fluorescent neurons in the cortical region surrounding infarction showed tetrodotoxin-sensitive Na(+) action potentials and spontaneous excitatory post-synaptic currents, suggesting that ischemia led to functional neurogenesis with synaptic integration, and support the hypothesis that enhancing endogenous neuroGenesis after stroke might have therapeutic benefit.
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Neuroglobin expression in neurogenesis
Bryan Haines,Xiao Ou Mao,Lin Xie,Steven C. Spusta,Xianmin Zeng,Kunlin Jin,Kunlin Jin,David A. Greenberg +7 more
TL;DR: It is suggested that neuroglobin is expressed early in the course of neuronal differentiation and may, therefore, have a role in neurodevelopment.
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SDF-1/CXCR7 Chemokine Signaling is Induced in the Peri-Infarct Regions in Patients with Ischemic Stroke.
Yu Zhang,Hongxia Zhang,Siyang Lin,Xudong Chen,Yu Yao,Xiao Ou Mao,Bei Shao,Qichuan Zhuge,Kunlin Jin,Kunlin Jin +9 more
TL;DR: The findings suggest that chemokine SFD-1 is expressed not only in animal models of stroke, but also in the human brain after an ischemic injury.
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Neuroglobin Overexpression Inhibits AMPK Signaling and Promotes Cell Anabolism
Bin Cai,Bin Cai,Wenjun Li,Xiao Ou Mao,Ali Winters,Myoung-Gwi Ryou,Ran Liu,David A. Greenberg,Ning Wang,Kunlin Jin,Shao-Hua Yang,Shao-Hua Yang +11 more
TL;DR: Increased ATP production and decreased glycolysis are found in Ngb-overexpressing immortalized murine hippocampal cell line (HT-22), in parallel with inhibition of AMP-activated protein kinase (AMPK) signaling and activation of acetyl-CoA carboxylase (ACC).