Xiao Ou Mao

TL;DR: It is reported that in patients with stroke, cells that express markers associated with newborn neurons are present in the ischemic penumbra surrounding cerebral cortical infarcts, where these cells are preferentially localized in the vicinity of blood vessels.

TL;DR: The results indicate that after cerebral ischemia, new neurons are directed toward sites of brain injury, where they might be in a position to participate in brain repair and functional recovery.

TL;DR: The effect of AD on neurogenesis can be reproduced in a transgenic mouse model and it seems to be caused by the disease itself and not by confounding clinical factors, which suggests that Neurogenesis may be a compensatory response and that measures to enhance neuroGenesis further could have therapeutic potential.

TL;DR: It is demonstrated that the aged brain retains the capacity to respond to exogenous growth factors with increased neurogenesis, which may have implications for the therapeutic potential of neuroGenesis enhancement in age‐associated neurological disorders.

TL;DR: In this article, the discovery that neuroglobin expression helps promote neuronal survival from hypoxic-ischemic insults was made, which is a good target to screen for agents that mitigate harmful effects from hypoxia/ischemics insults.